World Health Organization. WHO technical report series no. 923. Rheumatic Fever and Rheumatic Heart Disease. 2004. Available at https://www.who.int/cardiovascular_diseases/publications/trs923/en/.
World Health Organization. Seventy-First World Health Assembly. Provisional agenda item 12.8. Rheumatic fever and rheumatic heart disease. Report by the Director-General. April 12, 2018. Available at https://apps.who.int/gb/ebwha/pdf_files/WHA71/A71_25-en.pdf.
Parks T, Smeesters PR, Steer AC. Streptococcal skin infection and rheumatic heart disease. Curr Opin Infect Dis. 2012 Apr. 25(2):145-53. [QxMD MEDLINE Link].
Wannamaker LW. Differences between streptococcal infections of the throat and of the skin. I. N Engl J Med. 1970 Jan 1. 282(1):23-31. [QxMD MEDLINE Link].
Garcia AF, Yamaga KM, Shafer LA, et al. Cardiac myosin epitopes recognized by autoantibody in acute and convalescent rheumatic fever. Pediatr Infect Dis J. 2016 Sep. 35(9):1021-6. [QxMD MEDLINE Link]. [Full Text].
Group A streptococcal infections. Kimberlin DW, Brady MT, Jackson MA, Long SS, eds. Red Book: 2018-2021 Report of the Committee on Infectious Diseases. 31st ed. Itasca, IL: American Academy of Pediatrics; 2018. 748-62.
Anam A, Faisal AWK, Afzal N, Shahzad F. Immune system activation in rheumatic heart disease. J Coll Physicians Surg Pak. 2018 Jul. 28(7):518-22. [QxMD MEDLINE Link].
Lanna CC, Tonelli E, Barros MV, Goulart EM, Mota CC. Subclinical rheumatic valvitis: a long-term follow-up. Cardiol Young. 2003 Oct. 13(5):431-8. [QxMD MEDLINE Link].
Rocha Araujo FD, Brandao KN, Araujo FA, Vasconcelos Severiano GM, Alves Meira ZM. Cardiac tamponade as a rare form of presentation of rheumatic carditis. Am Heart Hosp J. 2010 Summer. 8(1):55-7. [QxMD MEDLINE Link].
Zühlke L, Engel ME, Karthikeyan G, et al. Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study). Eur Heart J. 2015 May 7. 36(18):1115-22a. [QxMD MEDLINE Link]. [Full Text].
Guilherme L, Ramasawmy R, Kalil J. Rheumatic fever and rheumatic heart disease: genetics and pathogenesis. Scand J Immunol. 2007 Aug-Sep. 66(2-3):199-207. [QxMD MEDLINE Link]. [Full Text].
Gomaa MH, Ali SS, Fattouh AM, Hamza HS, Badr MM. MBL2 gene polymorphism rs1800450 and rheumatic fever with and without rheumatic heart disease: an Egyptian pilot study. Pediatr Rheumatol Online J. 2018 Apr 13. 16(1):24. [QxMD MEDLINE Link]. [Full Text].
Mukhopadhyay S, Varma S, Gade S, Yusuf J, Trehan V, Tyagi S. Regulatory T-cell deficiency in rheumatic heart disease: a preliminary observational study. J Heart Valve Dis. 2013 Jan. 22(1):118-25. [QxMD MEDLINE Link].
Bas HD, Baser K, Yavuz E, et al. A shift in the balance of regulatory T and T helper 17 cells in rheumatic heart disease. J Investig Med. 2014 Jan. 62(1):78-83. [QxMD MEDLINE Link].
Eriksson JG, Kajantie E, Phillips DI, Osmond C, Thornburg KL, Barker DJ. The developmental origins of chronic rheumatic heart disease. Am J Hum Biol. 2013 Sep-Oct. 25(5):655-8. [QxMD MEDLINE Link].
Pande S, Tewari P, Agarwal SK, et al. Evidence of apoptosis in right ventricular dysfunction in rheumatic mitral valve stenosis. Indian J Med Res. 2016 Nov. 144(5):718-24. [QxMD MEDLINE Link]. [Full Text].
Xiao P, Zhang K, Tao Z, et al. Bmi1 and BRG1 drive myocardial repair by regulating cardiac stem cell function in acute rheumatic heart disease. Exp Ther Med. 2017 Oct. 14(4):3812-6. [QxMD MEDLINE Link]. [Full Text].
Gumus G, Giray D, Bobusoglu O, Tamer L, Karpuz D, Hallioglu O. MicroRNA values in children with rheumatic carditis: a preliminary study. Rheumatol Int. 2018 Jul. 38(7):1199-1205. [QxMD MEDLINE Link].
Lu Q, Sun Y, Duan Y, et al. Comprehensive microRNA profiling reveals potential augmentation of the IL1 pathway in rheumatic heart valve disease. BMC Cardiovasc Disord. 2018 Mar 16. 18(1):53. [QxMD MEDLINE Link]. [Full Text].
Veasy LG, Wiedmeier SE, Orsmond GS, et al. Resurgence of acute rheumatic fever in the intermountain area of the United States. N Engl J Med. 1987 Feb 19. 316(8):421-7. [QxMD MEDLINE Link].
Breda L, Marzetti V, Gaspari S, Del Torto M, Chiarelli F, Altobelli E. Population-based study of incidence and clinical characteristics of rheumatic fever in Abruzzo, central Italy, 2000-2009. J Pediatr. 2012 May. 160(5):832-6.e1. [QxMD MEDLINE Link].
Bhatia S, Tariq A, Erande A, Malik S. Characteristics and temporal trends of patients diagnosed with acute rheumatic fever in the United States from 2001-2011. J Am Coll Cardiol. 2016 Apr. 67(13 Suppl):1892. [Full Text].
Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis. 2005 Nov. 5(11):685-94. [QxMD MEDLINE Link].
Tibazarwa KB, Volmink JA, Mayosi BM. Incidence of acute rheumatic fever in the world: a systematic review of population-based studies. Heart. 2008 Dec. 94(12):1534-40. [QxMD MEDLINE Link].
Watkins DA, Johnson CO, Colquhoun SM, et al. Global, regional, and national burden of rheumatic heart disease, 1990-2015. N Engl J Med. 2017 Aug 24. 377(8):713-722. [QxMD MEDLINE Link]. [Full Text].
Naghavi M, Wang H, Lozano R, et al, for the GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Jan 10. 385(9963):117-71. [QxMD MEDLINE Link]. [Full Text].
Seckeler MD, Hoke TR. The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease. Clin Epidemiol. 2011 Feb 22. 3:67-84. [QxMD MEDLINE Link]. [Full Text].
Morberg DP, Alzate Lopez YA, Moreira S, Prata N, Riley LW, Burroughs Pena MS. The rheumatic heart disease healthcare paradox: disease persistence in slums despite universal healthcare coverage-a provider perspective qualitative study. Public Health. 2019 Jun. 171:15-23. [QxMD MEDLINE Link].
[Guideline] Gewitz MH, Baltimore RS, Tani LY, et al, for the American Heart Association Committee on Rheumatic Fever, Endocarditis, et al. Revision of the Jones Criteria for the diagnosis of acute rheumatic fever in the era of Doppler echocardiography: a scientific statement from the American Heart Association. Circulation. 2015 May 19. 131(20):1806-18. [QxMD MEDLINE Link]. [Full Text].
Minich LL, Tani LY, Pagotto LT, Shaddy RE, Veasy LG. Doppler echocardiography distinguishes between physiologic and pathologic "silent" mitral regurgitation in patients with rheumatic fever. Clin Cardiol. 1997 Nov. 20(11):924-6. [QxMD MEDLINE Link].
Pathania M, Rathaur VK, Pattupara AJ, Arya S, Bansal S, Kaeley N. Epistaxis as the initial presentation in a case of rheumatic heart disease. J Family Med Prim Care. 2018 Sep-Oct. 7(5):1136-8. [QxMD MEDLINE Link]. [Full Text].
Attar A, Marzban P, Moaref A, Aghasadeghi K. The association of plasma high-sensitivity C-reactive protein level with rheumatic heart disease: the possible role of inflammation. Indian Heart J. 2018 May - Jun. 70(3):346-9. [QxMD MEDLINE Link]. [Full Text].
Khare R, Dwivedi S. NT-ProBNP as a potential marker of left atrial dysfunction in rheumatic mitral stenosis: correlation with left atrial function after PBMV. J Heart Valve Dis. 2016 Sep. 25(5):613-8. [QxMD MEDLINE Link].
Sarkar S, Rastogi M, Chaudhary P, et al. Association of rheumatic fever & rheumatic heart disease with plausible early & late-stage disease markers. Indian J Med Res. 2017 Jun. 145(6):758-66. [QxMD MEDLINE Link]. [Full Text].
Yusuf J, Jothinath P, Mukhopadhyay S, Vignesh V, Tyagi S. Evaluation of serum 25-hydroxyvitamin D levels in calcific rheumatic mitral stenosis- A cross sectional study. Indian Heart J. 2018 Mar-Apr. 70(2):206-213. [QxMD MEDLINE Link]. [Full Text].
[Guideline] Remenyi B, Wilson N, Steer A, et al. World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline. Nat Rev Cardiol. 2011. 9(5):297-309. [QxMD MEDLINE Link]. [Full Text].
Marijon E, Ou P, Celermajer DS, et al. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007 Aug 2. 357(5):470-6. [QxMD MEDLINE Link]. [Full Text].
Nunes MCP, Sable C, Nascimento BR, et al. Simplified echocardiography screening criteria for diagnosing and predicting progression of latent rheumatic heart disease. Circ Cardiovasc Imaging. 2019 Feb. 12(2):e007928. [QxMD MEDLINE Link]. [Full Text].
Beaton A, Aliku T, Okello E, et al. The utility of handheld echocardiography for early diagnosis of rheumatic heart disease. J Am Soc Echocardiogr. 2014 Jan. 27(1):42-9. [QxMD MEDLINE Link].
Godown J, Lu JC, Beaton A, et al. Handheld echocardiography versus auscultation for detection of rheumatic heart disease. Pediatrics. 2015 Apr. 135(4):e939-44. [QxMD MEDLINE Link]. [Full Text].
Ntusi NA. Cardiovascular magnetic resonance imaging in rheumatic heart disease. Cardiovasc J Afr. 2018 May/Jun. 29(3):135-6. [QxMD MEDLINE Link]. [Full Text].
[Guideline] Wilson W, Taubert KA, Gewitz M, et al, for the American Heart Association. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. J Am Dent Assoc. 2008 Jan. 139 Suppl:3S-24S. [QxMD MEDLINE Link]. [Full Text].
American Heart Association. Infective endocarditis. Available at https://www.heart.org/en/health-topics/infective-endocarditis. Accessed: November 30, 2019.
[Guideline] Dajani AS, Ayoub E, Bierman FZ, et al. Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association. JAMA. 1992 Oct 21. 268(15):2069-73. [QxMD MEDLINE Link].
Kaplan EL. The group A streptococcal upper respiratory tract carrier state: an enigma. J Pediatr. 1980 Sep. 97(3):337-45. [QxMD MEDLINE Link].
Cilliers A, Adler AJ, Saloojee H. Anti-inflammatory treatment for carditis in acute rheumatic fever. Cochrane Database Syst Rev. 2015 May 28. CD003176. [QxMD MEDLINE Link].
Veasy LG, Wiedmeier SE, Orsmond GS, et al. Resurgence of acute rheumatic fever in the intermountain area of the United States. N Engl J Med. 1987 Feb 19. 316(8):421-7. [QxMD MEDLINE Link].
Feinstein AR, Wood HF, Epstein JA, Taranta A, Simpson R, Tursky E. A controlled study of three methods of prophylaxis against streptococcal infection in a population of rheumatic children. II. Results of the first three years of the study, including methods for evaluating the maintenance of oral prophylaxis. N Engl J Med. 1959 Apr 2. 260(14):697-702. [QxMD MEDLINE Link].
[Guideline] Wilson W, Taubert KA, Gewitz M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007 Oct 9. 116(15):1736-54. [QxMD MEDLINE Link]. [Full Text].
Hand RM, Salman S, Newall N, et al. A population pharmacokinetic study of benzathine benzylpenicillin G administration in children and adolescents with rheumatic heart disease: new insights for improved secondary prophylaxis strategies. J Antimicrob Chemother. 2019 Jul 1. 74(7):1984-91. [QxMD MEDLINE Link]. [Full Text].
Mejia OAV, Antunes MJ, Goncharov M, et al. Predictive performance of six mortality risk scores and the development of a novel model in a prospective cohort of patients undergoing valve surgery secondary to rheumatic fever. PLoS One. 2018. 13(7):e0199277. [QxMD MEDLINE Link]. [Full Text].
Inoue K, Owaki T, Nakamura T, Kitamura F, Miyamoto N. Clinical application of transvenous mitral commissurotomy by a new balloon catheter. J Thorac Cardiovasc Surg. 1984 Mar. 87(3):394-402. [QxMD MEDLINE Link].
Shrivastava S, Dev V, Vasan RS, et al. Percutaneous balloon mitral valvuloplasty in juvenile rheumatic mitral stenosis. Am J Cardiol. 1991 Apr 15. 67(9):892-4. [QxMD MEDLINE Link].
Talwar S, Rajesh MR, Subramanian A, et al. Mitral valve repair in children with rheumatic heart disease. J Thorac Cardiovasc Surg. 2005 Apr. 129(4):875-9. [QxMD MEDLINE Link].
Nezafati MH, Nezafati P, Hosseinzadeh M, Tehrani SO. Minimally invasive mitral valve surgery via minithoracotomy and direct cannulation. Asian Cardiovasc Thorac Ann. 2015 Mar. 23(3):271-4. [QxMD MEDLINE Link].
Sarkar A, Patil S, Ahmed I. Balloon mitral valvotomy in youngest documented rheumatic mitral stenosis patient. Catheter Cardiovasc Interv. 2015 Nov. 86(5):E213-6. [QxMD MEDLINE Link].
Yakub MA, Dillon J, Krishna Moorthy PS, Pau KK, Nordin MN. Is rheumatic aetiology a predictor of poor outcome in the current era of mitral valve repair? Contemporary long-term results of mitral valve repair in rheumatic heart disease. Eur J Cardiothorac Surg. 2013 Oct. 44(4):673-81. [QxMD MEDLINE Link].
[Guideline] Armstrong C. AHA guidelines on prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis. American Family Physician. 2010 Feb 1. 18(3):346-59.
Gandhi GD, Krishnamoorthy N, Motal UMA, Yacoub M. Towards developing a vaccine for rheumatic heart disease. Glob Cardiol Sci Pract. 2017 Mar 31. 2017(1):e201704. [QxMD MEDLINE Link]. [Full Text].
Group A streptococcal infections. Pickering LK, Baker CJ, Kimberlin DW, Long SS, eds. Red Book: 2009 Report of the Committee on Infectious Diseases. 28th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2009. 616-28.
Abernethy M, Bass N, Sharpe N, et al. Doppler echocardiography and the early diagnosis of carditis in acute rheumatic fever. Aust N Z J Med. 1994 Oct. 24(5):530-5. [QxMD MEDLINE Link].
Asbahr FR, Garvey MA, Snider LA, et al. Obsessive-compulsive symptoms among patients with Sydenham chorea. Biol Psychiatry. 2005 May 1. 57(9):1073-6. [QxMD MEDLINE Link].
Braunwald E. Rheumatic fever. Heart Disease: A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia, Pa: WB Saunders Co; 1997.
Carapetis JR, McDonald M, Wilson NJ. Acute rheumatic fever. Lancet. 2005 Jul 9-15. 366(9480):155-68. [QxMD MEDLINE Link].
Cilliers AM, Manyemba J, Saloojee H. Anti-inflammatory treatment for carditis in acute rheumatic fever. Cochrane Database Syst Rev. 2003. CD003176. [QxMD MEDLINE Link].
Rheumatic Fever Working Party of the Medical Research Council of Great Britain and the Subcommittee of Principal Investigators of the American Council on Rheumatic Fever and Congenital Heart Disease, American Heart Association. The natural history of rheumatic fever and rheumatic heart disease. Ten-year report of a cooperative clinical trial of ACTH, cortisone, and aspirin. Circulation. 1965 Sep. 32(3):457-76. [QxMD MEDLINE Link].
Cotran RS, Kumar V, Collins T, Robbins SL. Robbins Pathologic Basis of Disease. 6th ed. Philadelphia, Pa: WB Saunders Co; 1999.
Dajani A, Taubert K, Ferrieri P, Peter G, Shulman S. Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association. Pediatrics. 1995 Oct. 96(4 Pt 1):758-64. [QxMD MEDLINE Link].
Doshi H, Shukla V, Korula RJ. Emergency valve replacement in rheumatic heart disease. J Heart Valve Dis. 2003 Jul. 12(4):516-9. [QxMD MEDLINE Link].
Ellis NM, Li Y, Hildebrand W, Fischetti VA, Cunningham MW. T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease. J Immunol. 2005 Oct 15. 175(8):5448-56. [QxMD MEDLINE Link]. [Full Text].
Fae KC, Oshiro SE, Toubert A, Charron D, Kalil J, Guilherme L. How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease. J Autoimmun. 2005 Mar. 24(2):101-9. [QxMD MEDLINE Link].
Guilherme L, Fae K, Oshiro SE, Kalil J. Molecular pathogenesis of rheumatic fever and rheumatic heart disease. Expert Rev Mol Med. 2005 Dec 8. 7(28):1-15. [QxMD MEDLINE Link].
Massell BF, Fyler DC, Roy SB. The clinical picture of rheumatic fever: diagnosis, immediate prognosis, course, and therapeutic implications. Am J Cardiol. 1958 Apr. 1(4):436-49. [QxMD MEDLINE Link].
Narula J, Virmani R, Reddy KS, Tandon R. Rheumatic Fever. Washington DC: American Registry of Pathology; 1999.
Orun UA, Ceylan O, Bilici M, et al. Acute rheumatic fever in the Central Anatolia Region of Turkey: a 30-year experience in a single center. Eur J Pediatr. 2012 Feb. 171(2):361-8. [QxMD MEDLINE Link].
Rimoin AW, Hamza HS, Vince A, et al. Evaluation of the WHO clinical decision rule for streptococcal pharyngitis. Arch Dis Child. 2005 Oct. 90(10):1066-70. [QxMD MEDLINE Link].
Robertson KA, Volmink JA, Mayosi BM. Antibiotics for the primary prevention of acute rheumatic fever: a meta-analysis. BMC Cardiovasc Disord. 2005 May 31. 5(1):11. [QxMD MEDLINE Link].
Sampaio RO, Grinberg M, Leite JJ, et al. Effect of enalapril on left ventricular diameters and exercise capacity in asymptomatic or mildly symptomatic patients with regurgitation secondary to mitral valve prolapse or rheumatic heart disease. Am J Cardiol. 2005 Jul 1. 96(1):117-21. [QxMD MEDLINE Link].
Swedo SE, Leonard HL, Garvey M, et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases [published erratum appears in Am J Psychiatry 1998 Apr;155(4):578]. Am J Psychiatry. 1998 Feb. 155(2):264-71. [QxMD MEDLINE Link].
Walker KG, Lawrenson J, Wilmshurst JM. Neuropsychiatric movement disorders following streptococcal infection. Dev Med Child Neurol. 2005 Nov. 47(11):771-5. [QxMD MEDLINE Link].
Zegeye N, Asrat D, Woldeamanuel Y, et al. Throat culture positivity rate and antibiotic susceptibility pattern of beta-hemolytic streptococci in children on secondary prophylaxis for rheumatic heart disease. BMC Infect Dis. 2016 Sep 23. 16(1):510. [QxMD MEDLINE Link]. [Full Text].
Carapetis JR, Beaton A, Cunningham MW, et al. Acute rheumatic fever and rheumatic heart disease. Nat Rev Dis Primers. 2016 Jan 14. 2:15084. [QxMD MEDLINE Link]. [Full Text].
Parnaby MG, Carapetis JR. Rheumatic fever in indigenous Australian children. J Paediatr Child Health. 2010 Sep. 46(9):527-33. [QxMD MEDLINE Link].
Hashkes PJ, Tauber T, Somekh E, et al, for the Pediatric Rheumatology Study Group of Israel. Naproxen as an alternative to aspirin for the treatment of arthritis of rheumatic fever: a randomized trial. J Pediatr. 2003 Sep. 143(3):399-401. [QxMD MEDLINE Link].
Gerber MA, Baltimore RS, Eaton CB, et al. Prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation. 2009 Mar 24. 119(11):1541-51. [QxMD MEDLINE Link]. [Full Text].
[Guideline] Nishimura RA, Otto CM, Bonow RO, et al, for the American College of Cardiology, American College of Cardiology/American Heart Association, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014 Jun 10. 129(23):e521-643. [QxMD MEDLINE Link]. [Full Text].
[Guideline] Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017 Jun 20. 135(25):e1159-95. [QxMD MEDLINE Link]. [Full Text].
