Coronary Sinus Atrial Septal Defects Medication

Updated: Jul 03, 2019
  • Author: Louis I Bezold, MD; Chief Editor: Syamasundar Rao Patnana, MD  more...
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Medication Summary

Medications include diuretics, digoxin, and various antiarrhythmics medications.

Diuretics and digoxin may be used in the management of congestive heart failure associated with large left-to-right shunts in patients with atrial septal defects (ASDs).


Diuretics, loop

Class Summary

These agents are used to treat pulmonary overcirculation associated with left-to-right atrial level shunt. They promote excretion of water and electrolytes by the kidneys. They are used to treat heart failure or hepatic, renal, or pulmonary disease when sodium and water retention results in edema or ascites.

Furosemide (Lasix)

Increases excretion of water by interfering with chloride-binding cotransport system, which, in turn, inhibits sodium and chloride reabsorption in ascending loop of Henle and distal renal tubule. Dose uptitrated to effect; low dose usually adequate.


Cardiac glycosides, antiarrhythmic agents

Class Summary

These agents are used to treat congestive heart failure and slow the ventricular response in atrial fibrillation or flutter.

Digoxin (Lanoxin, Lanoxicaps)

Positive inotropic effect related to increased cellular influx of calcium ions by inhibiting sodium-potassium exchange. Decreases conduction through sinoatrial and atrioventricular nodes.