Medial Synovial Plica Irritation Medication

Updated: Jul 22, 2022
  • Author: Robert F LaPrade, MD, PhD; Chief Editor: Craig C Young, MD  more...
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Medication Summary

Any of the nonsteroidal anti-inflammatory drugs (NSAIDs) may be used to try to supplement the physical therapy program. Generally, it is recommended to start with over-the-counter (OTC) NSAIDs first. If these agents do not work, or if they work only in the maximum doses, prescription drugs may be utilized based upon the patient's previous success with these medications, drug allergies, or other medications.


Nonsteroidal anti-inflammatory agents

Class Summary

NSAIDs have analgesic, anti-inflammatory, and antipyretic activities. Their mechanism of action is not known, but these agents may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions.

Ibuprofen (Motrin, Ibuprin)

An OTC NSAID that is useful to decrease pain and inflammation. DOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.