Posterior Cruciate Ligament Injury Medication

Updated: Aug 11, 2022
  • Author: Charles S Peterson, MD; Chief Editor: Craig C Young, MD  more...
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Medication

Medication Summary

Medications are used in cases of PCL injuries for pain control, inflammation, and swelling. Pain medications are used as indicated for acute pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to control inflammation and swelling.

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Narcotic analgesics

Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort and have sedating properties, which are beneficial for patients who have sustained trauma or injuries.

Acetaminophen and codeine (Tylenol #3)

Indicated for the treatment of mild to moderate pain.

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Nonsteroidal anti-inflammatory drugs

Class Summary

Have analgesic, anti-inflammatory, and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclo-oxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions.

Ibuprofen (Motrin, Ibuprin)

DOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Ketoprofen (Actron, Oruvail, Orudis)

For relief of mild to moderate pain and inflammation. Small dosages initially are indicated in small and elderly patients and in those with renal or liver disease. Doses larger than 75 mg do not increase therapeutic effects. Administer high doses with caution, and closely observe patient for response.

Naproxen (Anaprox, Naprosyn, Naprelan)

For relief of mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing activity of cyclo-oxygenase, which results in a decrease of prostaglandin synthesis.

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