Pediatric Metabolic Acidosis Differential Diagnoses

Updated: Dec 31, 2019
  • Author: Lennox H Huang, MD, FAAP; Chief Editor: Timothy E Corden, MD  more...
  • Print
DDx

Diagnostic Considerations

Approach considerations

Other conditions to consider in the diagnosis of metabolic acidosis, along with those in the next section, include the following:

  • Renal tubular acidosis

  • Lactic acidosis

  • Cyanide toxicity

  • Ethylene glycol toxicity

  • Methanol toxicity

  • Dilated cardiomyopathy

  • Chronic kidney disease

  • Coarctation of the aorta

  • Dehydration

  • Ornithine transcarbamylase deficiency

  • Phenylketonuria

  • Pneumococcal bacteremia

  • Sepsis

  • Toxic shock syndrome

  • Diarrhea

  • Hyperammonemia

  • Hypoplastic left heart syndrome

  • Interrupted aortic arch

  • Intestinal volvulus

  • Neonatal sepsis

  • Neuroleptic malignant syndrome

  • Isoniazid toxicity

  • Salicylate toxicity

  • Meningococcal infections

  • Diabetic ketoacidosis

Differential Diagnoses