Pediatric Head Trauma Differential Diagnoses

1. Ringl H, Schernthaner R, Philipp MO, et al. Three-dimensional fracture visualisation of multidetector CT of the skull base in trauma patients: comparison of three reconstruction algorithms. Eur Radiol. 2009 Oct. 19(10):2416-24. [Medline].

2. Rabiner JE, Friedman LM, Khine H, Avner JR, Tsung JW. Accuracy of point-of-care ultrasound for diagnosis of skull fractures in children. Pediatrics. 2013 Jun. 131(6):e1757-64. [Medline]. [Full Text].

3. Cakmakci H. Essentials of trauma: head and spine. Pediatr Radiol. 2009 Jun. 39 suppl 3:391-405. [Medline].

4. Sarioglu FC, Sahin H, Pekcevik Y, Sarioglu O, Oztekin O. Pediatric head trauma: an extensive review on imaging requisites and unique imaging findings. Eur J Trauma Emerg Surg. 2017 Sep 15. [Medline].

5. Quayle KS, Powell EC, Mahajan P, et al. Epidemiology of blunt head trauma in children in U.S. emergency departments [letter]. N Engl J Med. 2014 Nov 13. 371(20):1945-7. [Medline]. [Full Text].

6. Guilliams K, Wainwright MS. Pathophysiology and management of moderate and severe traumatic brain injury in children. J Child Neurol. 2016 Jan. 31(1):35-45. [Medline].

7. Toda N, Ayajiki K, Okamura T. Cerebral blood flow regulation by nitric oxide: recent advances. Pharmacol Rev. 2009 Mar. 61(1):62-97. [Medline].

8. Yeates KO, Taylor HG, Rusin J, et al. Longitudinal trajectories of postconcussive symptoms in children with mild traumatic brain injuries and their relationship to acute clinical status. Pediatrics. 2009 Mar. 123(3):735-43. [Medline].

9. Kelly P, Thompson JMD, Koh J, et al. Perinatal risk and protective factors for pediatric abusive head trauma: a multicenter case-control study. J Pediatr. 2017 Aug. 187:240-6.e4. [Medline].

10. Hymel KP, Stoiko MA, Herman BE, et al. Head injury depth as an indicator of causes and mechanisms. Pediatrics. 2010 Apr. 125(4):712-20. [Medline].

11. Allard RH, van Merkesteyn JP, Baart JA. [Child abuse]. Ned Tijdschr Tandheelkd. 2009 Apr. 116(4):186-91. [Medline].

12. Iranmanesh F. Outcome of head trauma. Indian J Pediatr. 2009 Sep. 76(9):929-31. [Medline].

13. Garcia Garcia JJ, Manrique Martinez I, Trenchs Sainz de la Maza V, et al for the Grupo de Trabajo de Trauma Craneal de la SEUP. [Registry of mild craniocerebral trauma: multicentre study from the Spanish Association of Pediatric emergencies]. An Pediatr (Barc). 2009 Jul. 71(1):31-7. [Medline].

14. Mackerle Z, Gal P. Unusual penetrating head injury in children: personal experience and review of the literature. Childs Nerv Syst. 2009 Aug. 25(8):909-13. [Medline].

15. Haider AH, Crompton JG, Oyetunji T, et al. Mechanism of injury predicts case fatality and functional outcomes in pediatric trauma patients: the case for its use in trauma outcomes studies. J Pediatr Surg. 2011 Aug. 46(8):1557-63. [Medline].

16. National Center for Health Statistics. National death index. Available at https://www.cdc.gov/nchs/. Accessed: December 18, 2017.

17. Shein SL, Bell MJ, Kochanek PM, et al. Risk factors for mortality in children with abusive head trauma. J Pediatr. 2012 Oct. 161(4):716-722.e1. [Medline].

18. Kapapa T, Pfister U, Konig K, et al. Head trauma in children, part 3: clinical and psychosocial outcome after head trauma in children. J Child Neurol. 2010 Apr. 25(4):409-22. [Medline].

19. Ley EJ, Srour MK, Clond MA, et al. Diabetic patients with traumatic brain injury: insulin deficiency is associated with increased mortality. J Trauma. 2011 May. 70(5):1141-4. [Medline].

20. Pinto PS, Poretti A, Meoded A, Tekes A, Huisman TA. The unique features of traumatic brain injury in children. Review of the characteristics of the pediatric skull and brain, mechanisms of trauma, patterns of injury, complications and their imaging findings--part 1. J Neuroimaging. 2012 Apr. 22(2):e1-e17. [Medline].

21. Pinto PS, Meoded A, Poretti A, Tekes A, Huisman TA. The unique features of traumatic brain injury in children. review of the characteristics of the pediatric skull and brain, mechanisms of trauma, patterns of injury, complications, and their imaging findings--part 2. J Neuroimaging. 2012 Apr. 22(2):e18-41. [Medline].

22. Prigatano GP, Gale SD. The current status of postconcussion syndrome. Curr Opin Psychiatry. 2011 May. 24(3):243-50. [Medline].

23. Dias MS, Rottmund CM, Cappos KM, et al. Association of a postnatal parent education program for abusive head trauma with subsequent pediatric abusive head trauma hospitalization rates. JAMA Pediatr. 2017 Mar 1. 171 (3):223-9. [Medline].

24. Rangarajan N, Kamalakkannan SB, Hasija V, et al. Finite element model of ocular injury in abusive head trauma. J AAPOS. 2009 Aug. 13(4):364-9. [Medline].

25. [Guideline] First comprehensive pediatric concussion guidelines, available now. Medical Xpress. Available at http://medicalxpress.com/news/2014-06-comprehensive-pediatric-concussion-guidelines.html. June 25, 2014; Accessed: July 2, 2014.

26. Brunelle C, Hennecker JL, Scordidis V. [Loss of consciousness after a minor trauma revealing an aneurysm rupture in a child]. Arch Pediatr. 2012 Aug. 19(8):815-8. [Medline].

27. Chelly H, Chaari A, Daoud E, et al. Diffuse axonal injury in patients with head injuries: an epidemiologic and prognosis study of 124 cases. J Trauma. 2011 Oct. 71(4):838-46. [Medline].

28. Maguire SA, Kemp AM, Lumb RC, Farewell DM. Estimating the probability of abusive head trauma: a pooled analysis. Pediatrics. 2011 Sep. 128(3):e550-64. [Medline].

29. Leeper CM, Nasr I, McKenna C, Berger RP, Gaines BA. Elevated admission international normalized ratio strongly predicts mortality in victims of abusive head trauma. J Trauma Acute Care Surg. 2016 May. 80 (5):711-6. [Medline].

30. Manzano S, Holzinger IB, Kellenberger CJ, et al. Diagnostic performance of S100B protein serum measurement in detecting intracranial injury in children with mild head trauma. Emerg Med J. 2016 Jan. 33(1):42-6. [Medline].

31. Papa L, Mittal MK, Ramirez J, et al. In children and youth with mild and moderate traumatic brain injury, glial fibrillary acidic protein out-performs s100β in detecting traumatic intracranial lesions on computed tomography. J Neurotrauma. 2016 Jan 1. 33(1):58-64. [Medline].

32. Kuppermann N, Holmes JF, Dayan PS, et al. Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study. Lancet. 2009 Oct 3. 374(9696):1160-70. [Medline].

33. Sellin JN, Moreno A, Ryan SL, et al. Children presenting in delayed fashion after minor head trauma with scalp swelling: do they require further workup?. Childs Nerv Syst. 2017 Apr. 33 (4):647-52. [Medline].

34. Kochanek PM, Carney N, Adelson PD, et al. Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. Pediatr Crit Care Med. 2012 Jan. 13 Suppl 1:S1-82. [Medline].

35. Kralik SF, Yasrebi M, Supakul N, et al. Diagnostic performance of ultrafast brain MRI for evaluation of abusive head trauma. AJNR Am J Neuroradiol. 2017 Apr. 38 (4):807-13. [Medline].

36. [Guideline] Christian CW, Committee on Child Abuse and Neglect, American Academy of Pediatrics. The evaluation of suspected child physical abuse. Pediatrics. 2015 May. 135 (5):e1337-54. [Medline].

37. Holmes JF, Borgialli DA, Nadel FM, et al. Do children with blunt head trauma and normal cranial computed tomography scan results require hospitalization for neurologic observation?. Ann Emerg Med. 2011 Oct. 58(4):315-22. [Medline].

38. Thomas M, Haas TS, Doerer JJ, et al. Epidemiology of sudden death in young, competitive athletes due to blunt trauma. Pediatrics. 2011 Jul. 128(1):e1-8. [Medline].

39. Robinson N, Clancy M. In patients with head injury undergoing rapid sequence intubation, does pretreatment with intravenous lignocaine/lidocaine lead to an improved neurological outcome? A review of the literature. Emerg Med J. 2001 Nov. 18(6):453-7. [Medline]. [Full Text].

40. Haque IU, Zaritsky AL. Analysis of the evidence for the lower limit of systolic and mean arterial pressure in children. Pediatr Crit Care Med. 2007 Mar. 8(2):138-44. [Medline].

41. Brown CV, Sowery L, Curry E, et al. Recombinant factor VIIa to correct coagulopathy in patients with traumatic brain injury presenting to outlying facilities before transfer to the regional trauma center. Am Surg. 2012 Jan. 78(1):57-60. [Medline].

42. [Guideline] Kellogg ND. Evaluation of suspected child physical abuse. Pediatrics. 2007 Jun. 119(6):1232-41. [Medline]. [Full Text].

43. Choe MC, Blume HK. Pediatric posttraumatic headache: a review. J Child Neurol. 2016 Jan. 31(1):76-85. [Medline].

44. Kralik SF, Finke W, Wu IC, Hibbard RA, Hicks RA, Ho CY. Radiologic head CT interpretation errors in pediatric abusive and non-abusive head trauma patients. Pediatr Radiol. 2017 Jul. 47 (8):942-51. [Medline].

45. Khan NR, Fraser BD, Nguyen V, et al. Pediatric abusive head trauma and stroke. J Neurosurg Pediatr. 2017 Aug. 20 (2):183-90. [Medline].

Michael J Verive, MD, FAAP Pediatrician, UP Health System Portage

Michael J Verive, MD, FAAP is a member of the following medical societies: American Academy of Pediatrics, Society for Pediatric Sedation

Disclosure: Nothing to disclose.

Arabela Stock, MD Consulting Staff, Department of Pediatrics, Division of Critical Care, All Children's Hospital

Arabela Stock, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians

Disclosure: Nothing to disclose.

Jagvir Singh, MD Director, Division of Pediatric Emergency Medicine, Lutheran General Hospital of Park Ridge

Jagvir Singh, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Kirsten A Bechtel, MD Associate Professor of Pediatrics, Section of Pediatric Emergency Medicine, Yale University School of Medicine; Co-Director, Injury Free Coalition for Kids, Yale-New Haven Children's Hospital

Kirsten A Bechtel, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Muhammad Waseem, MBBS, MS, FAAP, FACEP, FAHA Professor of Emergency Medicine and Clinical Pediatrics, Weill Cornell Medical College; Attending Physician, Departments of Emergency Medicine and Pediatrics, Lincoln Medical and Mental Health Center; Adjunct Professor of Emergency Medicine, Adjunct Professor of Pediatrics, St George's University School of Medicine, Grenada

Muhammad Waseem, MBBS, MS, FAAP, FACEP, FAHA is a member of the following medical societies: American Academy of Pediatrics, American Academy of Urgent Care Medicine, American College of Emergency Physicians, American Heart Association, American Medical Association, Association of Clinical Research Professionals, Public Responsibility in Medicine and Research, Society for Academic Emergency Medicine, Society for Simulation in Healthcare

Disclosure: Nothing to disclose.

Timothy E Corden, MD Associate Professor of Pediatrics, Co-Director, Policy Core, Injury Research Center, Medical College of Wisconsin; Associate Director, PICU, Children's Hospital of Wisconsin

Timothy E Corden, MD is a member of the following medical societies: American Academy of Pediatrics, Phi Beta Kappa, Society of Critical Care Medicine, Wisconsin Medical Society

Disclosure: Nothing to disclose.

G Patricia Cantwell, MD, FCCM Professor of Clinical Pediatrics, Chief, Division of Pediatric Critical Care Medicine, University of Miami, Leonard M Miller School of Medicine; Medical Director, Palliative Care Team, Director, Pediatric Critical Care Transport, Holtz Children's Hospital, Jackson Memorial Medical Center; Medical Manager, FEMA, Urban Search and Rescue, South Florida, Task Force 2; Pediatric Medical Director, Tilli Kids – Pediatric Initiative, Division of Hospice Care Southeast Florida, Inc

G Patricia Cantwell, MD, FCCM is a member of the following medical societies: American Academy of Hospice and Palliative Medicine, American Academy of Pediatrics, American Heart Association, American Trauma Society, National Association of EMS Physicians, Society of Critical Care Medicine, and Wilderness Medical Society

Disclosure: Nothing to disclose.

Barry J Evans, MD Assistant Professor of Pediatrics, Temple University Medical School; Director of Pediatric Critical Care and Pulmonology, Associate Chair for Pediatric Education, Temple University Children's Medical Center

Barry J Evans, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Chest Physicians, American Thoracic Society, and Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

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