Slipped Capital Femoral Epiphysis Medication

Updated: Dec 03, 2018
  • Author: Kevin D Walter, MD, FAAP; Chief Editor: Craig C Young, MD  more...
  • Print

Medication Summary

No medical therapy is available for the treatment of slipped capital femoral epiphysis (SCFE) except symptomatic pain relief. Medications may include acetaminophen, nonsteroidal anti-inflammatory drugs, or narcotics, depending on the physician's preference.



Class Summary

Pain control is essential to quality patient care. Analgesics ensure patient comfort and have sedating properties, which are beneficial for patients who have sustained trauma or who have sustained injuries.

Acetaminophen (Tylenol, Feverall, Tempra)

DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or who are taking oral anticoagulants.

Hydrocodone and acetaminophen (Vicodin, Lorcet, Lortab)

Drug combination for moderate to severe pain.

Codeine/acetaminophen (Tylenol With Codeine #2, #3, #4)

Indicated for mild to moderate pain. Opioid and analgesic.

Acetaminophen and codeine content of Tylenol products is as follows:

Tylenol #2: 300 mg acetaminophen/15 mg codeine

Tylenol #3: 300 mg acetaminophen/30 mg codeine

Tylenol #4: 300 mg acetaminophen/60 mg codeine


Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Class Summary

NSAIDs have analgesic, anti-inflammatory, and antipyretic activities, which make these ideal agents for treating ankle injuries. The mechanism of action of NSAIDs is not known, but they may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation and various cell membrane functions.

Ibuprofen (Motrin, Advil)

DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Ketoprofen (Orudis, Actron, Oruvail)

Indicated for mild to moderate pain and inflammation.

Small initial doses are indicated in small and elderly patients and in those with renal or liver disease.

Doses >75 mg do not increase the therapeutic effects. Administer high doses with caution, and closely observe the patient for the response.

Naproxen (Naprelan, Anaprox, Naprosyn)

Indicated for mild to moderate pain; inhibits inflammatory reactions and pain by decreasing the activity of cyclooxygenase, which results in a decrease of prostaglandin synthesis.