Glucocorticoid Therapy and Cushing Syndrome Differential Diagnoses

Updated: Mar 23, 2021
  • Author: George P Chrousos, MD, FAAP, MACP, MACE, FRCP(London); Chief Editor: Sasigarn A Bowden, MD, FAAP  more...
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Diagnostic Considerations

Other conditions to consider in the diagnosis of Cushing syndrome include the following:

  • Simple exogenous obesity

  • Hypothyroidism and growth hormone deficiency

  • Pseudohypoparathyroidism type 1a

  • Hypothalamic disorders

  • Pseudo-Cushing disease

Genetic obesity syndromes include the following:

  • Laurence-Moon syndrome (MIM 245800)

  • Bardet-Biedl syndrome, 6 types (chromosome arms 2q31; 3p13-p12; 11q13; 15q22.3-q23; 16q21; 20p12)

  • Smith-Magenis syndrome (MIM 182290; chromosome arm 17p11.2)

  • Alström syndrome (MIM 203800; chromosome arm 2p13)

  • Cherubism (MIM 118400; chromosome arm 4p16.3)

  • Prader-Willi syndrome (MIM 176270; chromosome arm 15q11-13)

Differential Diagnoses