Pediatric Multiple Endocrine Neoplasia Guidelines

Updated: Oct 11, 2017
  • Author: Alicia Diaz-Thomas, MD, MPH; Chief Editor: Robert P Hoffman, MD  more...
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Guidelines

Guidelines Summary

Clinical Practice Guidelines for (MEN) type 1 by the Endocrine Society recommend that testing for MEN1 germline mutation should be offered to patients with MEN1 and their first-degree relatives and that patients with MEN1 and their families should be managed by a multidisciplinary team that includes physicians who specialize in managing endocrine tumors. [19]  

Other Guidelines include:

  • Brandi ML, Gagel RF, Angeli A, et al. Guidelines for diagnosis and therapy of MEN type 1 and type 2. J Clin Endocrinol Metab. 2001 Dec;86(12):5658-71. [20]
  • Waguespack SG, Rich TA, Perrier ND, et al. Management of medullary thyroid carcinoma and MEN2 syndromes in childhood. Nat Rev Endocrinol. 2011 Aug 23;7(10):596-607. doi: 10.1038/nrendo.2011.139. [21]
  • Wells SA Jr, Asa SL, Dralle H, et al. American Thyroid Association Guidelines Task Force on Medullary Thyroid Carcinoma. Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. Thyroid. 2015 Jun;25(6):567-610. doi: 10.1089/thy.2014.0335. Review. [22]
  • Chen H, Sippel RS, O'Dorisio MS, et al. North American Neuroendocrine Tumor Society (NANETS). The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer. Pancreas. 2010 Aug;39(6):775-83. doi: 10.1097/MPA.0b013e3181ebb4f0. [23]