Panhypopituitarism Questions & Answers

Updated: Apr 29, 2018
  • Author: Robert P Hoffman, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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Questions & Answers

Overview

What is panhypopituitarism?

How is panhypopituitarism diagnosed and treated?

What is the pathophysiology of panhypopituitarism?

What is the prevalence of panhypopituitarism in the US?

What is the prognosis of panhypopituitarism?

Presentation

Which clinical history findings are characteristic of congenital hypopituitarism in panhypopituitarism?

Which clinical history findings are characteristic of acquired hypopituitarism in panhypopituitarism?

Which physical findings are characteristic of panhypopituitarism in neonates?

Which physical findings are characteristic of panhypopituitarism in older children?

What are the congenital causes of panhypopituitarism?

What are the acquired causes of panhypopituitarism?

DDX

What are the differential diagnoses for Panhypopituitarism?

Workup

What is included in the workup of panhypopituitarism?

How is thyroid-stimulating hormone (TSH) deficiency assessed in patients with panhypopituitarism?

How is adrenocorticotropic hormone (ACTH) deficiency assessed in patients with panhypopituitarism?

How is gonadotropin deficiency assessed in males with panhypopituitarism?

How is gonadotropin deficiency assessed in females with panhypopituitarism?

What is the role of gonadotropin-releasing hormone (GNRH) testing in the workup of panhypopituitarism?

How is growth hormone (GH) deficiency assessed in patients with panhypopituitarism?

What is the role of MRI in the workup of panhypopituitarism?

How is bone age determined in the workup of panhypopituitarism?

Treatment

How is adrenocorticotropic hormone (ACTH) deficiency treated in panhypopituitarism?

How is thyroid-stimulating hormone (TSH) deficiency treated in panhypopituitarism?

How is gonadotropin deficiency treated in panhypopituitarism?

How is growth hormone (GH) deficiency treated in panhypopituitarism?

What is the role of surgery in the treatment of panhypopituitarism?

Which specialist consultations are beneficial to patients with panhypopituitarism?

Medications

What are the goals of drug treatment for panhypopituitarism?

Which medications in the drug class Estrogen Derivative are used in the treatment of Panhypopituitarism?

Which medications in the drug class Hormones are used in the treatment of Panhypopituitarism?

Follow-up

What is included in long-term monitoring of panhypopituitarism?

What are the possible complications of panhypopituitarism treatment?

What is the prognosis of panhypopituitarism?

What is included in patient education about panhypopituitarism?