Thyroid Storm Questions & Answers

Updated: Feb 18, 2018
  • Author: Madhusmita Misra, MD, MPH; Chief Editor: Robert P Hoffman, MD  more...
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Questions & Answers

Overview

What is thyroid storm?

What is the pathophysiology of thyroid storm?

Which factors precipitate thyroid storm in thyrotoxicosis?

Which causes of thyrotoxicosis are associated with thyroid storm?

Which autoimmune conditions are associated with thyroid storm?

What is the pathogenesis of thyroid storm?

What is the prevalence of thyroid storm?

What are the sexual predilections of thyroid storm?

Which age groups have the highest prevalence of thyroid storm?

What is the prognosis of thyroid storm?

Which factors increase the mortality risk of thyroid storm?

Presentation

Which clinical history findings are characteristic of thyroid storm?

What are the general signs and symptoms of thyroid storm?

What are the GI signs and symptoms of thyroid storm?

What are the neurologic signs and symptoms of thyroid storm?

Which physical findings are characteristic of thyroid storm?

What are the possible complications of thyroid storm?

DDX

What are the differential diagnoses for Thyroid Storm?

Workup

How is thyroid storm diagnosed?

What is the role of lab tests in the workup of thyroid storm?

What is the role of imaging studies in the workup of thyroid storm?

What is the role of ECG in the workup of thyroid storm?

Treatment

How is thyroid storm treated?

Which supportive measures are used in the treatment of thyroid storm?

What is the role of antiadrenergic drugs (propranolol) in thyroid storm treatment?

What is the dosing of beta-blockers for the treatment of pediatric thyroid storm?

What is the role of thionamides in thyroid storm treatment?

What is the role of iodine compounds in thyroid storm treatment?

What is the role of glucocorticoids in thyroid storm treatment?

What is the role of bile acid sequestrants in thyroid storm treatment?

Which underlying conditions must be treated during thyroid storm?

What is the role of plasmapheresis in thyroid storm treatment?

When are medications discontinued in thyroid storm treatment?

How is thyroid storm treated in patients with a contraindication to thionamides?

How is thyroid storm treated in patients with Graves disease and a contraindication to thionamides?

What is the role of surgery in the treatment of thyroid storm?

Which specialist consultations are beneficial to patients with thyroid storm?

How is thyroid storm prevented?

Guidelines

What are the Japan Thyroid Association and Japan Endocrine Society treatment guidelines for thyroid storm?

Medications

Which medications are used in thyroid storm treatment?

Which medications in the drug class Glucocorticoids are used in the treatment of Thyroid Storm?

Which medications in the drug class Beta- blockers are used in the treatment of Thyroid Storm?

Which medications in the drug class Iodides are used in the treatment of Thyroid Storm?

Which medications in the drug class Antithyroids are used in the treatment of Thyroid Storm?