Pediatric Appendicitis Questions & Answers

1. Narsule CK, Kahle EJ, Kim DS, Anderson AC, Luks FI. Effect of delay in presentation on rate of perforation in children with appendicitis. Am J Emerg Med. 2011 Oct. 29(8):890-3. [QxMD MEDLINE Link].

2. Rothrock SG, Pagane J. Acute appendicitis in children: emergency department diagnosis and management. Ann Emerg Med. 2000 Jul. 36(1):39-51. [QxMD MEDLINE Link].

3. Becker T, Kharbanda A, Bachur R. Atypical clinical features of pediatric appendicitis. Acad Emerg Med. 2007 Feb. 14(2):124-9. [QxMD MEDLINE Link].

4. Wiersma F, Toorenvliet BR, Bloem JL, Allema JH, Holscher HC. US examination of the appendix in children with suspected appendicitis: the additional value of secondary signs. Eur Radiol. 2009 Feb. 19(2):455-61. [QxMD MEDLINE Link].

5. Pastore V, Cocomazzi R, Basile A, Pastore M, Bartoli F. Limits and advantages of abdominal ultrasonography in children with acute appendicitis syndrome. Afr J Paediatr Surg. 2014 Oct-Dec. 11(4):293-6. [QxMD MEDLINE Link].

6. Gracey D, McClure MJ. The impact of ultrasound in suspected acute appendicitis. Clin Radiol. 2007 Jun. 62(6):573-8. [QxMD MEDLINE Link].

7. Sulowski C, Doria AS, Langer JC, Man C, Stephens D, Schuh S. clinical outcomes in obese and normal-weight children undergoing ultrasound for suspected appendicitis. Acad Emerg Med. 2011 Feb. 18(2):167-73. [QxMD MEDLINE Link].

8. Lowe LH, Penney MW, Stein SM, et al. Unenhanced limited CT of the abdomen in the diagnosis of appendicitis in children: comparison with sonography. AJR Am J Roentgenol. 2001 Jan. 176(1):31-5. [QxMD MEDLINE Link].

9. Bachur RG, Levy JA, Callahan MJ, Rangel SJ, Monuteaux MC. Effect of Reduction in the Use of Computed Tomography on Clinical Outcomes of Appendicitis. JAMA Pediatr. 2015 Aug 1. 169 (8):755-60. [QxMD MEDLINE Link].

10. Peck J, Peck A, Peck C, Peck J. The clinical role of noncontrast helical computed tomography in the diagnosis of acute appendicitis. Am J Surg. 2000 Aug. 180(2):133-6. [QxMD MEDLINE Link].

11. Anderson KT, Putnam LR, Caldwell KM, B Diffley M, A Hildebrandt A, Covey SE, et al. Imaging gently? Higher rates of computed tomography imaging for pediatric appendicitis in non-children's hospitals. Surgery. 2017 May. 161 (5):1326-1333. [QxMD MEDLINE Link].

12. Muehlstedt SG, Pham TQ, Schmeling DJ. The management of pediatric appendicitis: a survey of North American Pediatric Surgeons. J Pediatr Surg. 2004 Jun. 39 (6):875-9; discussion 875-9. [QxMD MEDLINE Link].

13. Mullins ME, Kircher MF, Ryan DP, et al. Evaluation of suspected appendicitis in children using limited helical CT and colonic contrast material. AJR Am J Roentgenol. 2001 Jan. 176(1):37-41. [QxMD MEDLINE Link].

14. Callahan MJ, Rodriguez DP, Taylor GA. CT of appendicitis in children. Radiology. 2002 Aug. 224(2):325-32. [QxMD MEDLINE Link].

15. Kharbanda AB, Taylor GA, Fishman SJ, Bachur RG. A clinical decision rule to identify children at low risk for appendicitis. Pediatrics. 2005 Sep. 116(3):709-16. [QxMD MEDLINE Link].

16. Samuel M. Pediatric appendicitis score. J Pediatr Surg. 2002 Jun. 37(6):877-81. [QxMD MEDLINE Link].

17. Schneider C, Kharbanda A, Bachur R. Evaluating appendicitis scoring systems using a prospective pediatric cohort. Ann Emerg Med. 2007 Jun. 49(6):778-84, 784.e1. [QxMD MEDLINE Link].

18. Kronman MP, Oron AP, Ross RK, Hersh AL, Newland JG, Goldin A, et al. Extended- Versus Narrower-Spectrum Antibiotics for Appendicitis. Pediatrics. 2016 Jul. 138 (1):[QxMD MEDLINE Link].

19. Whyte C, Tran E, Lopez ME, Harris BH. Outpatient interval appendectomy after perforated appendicitis. J Pediatr Surg. 2008 Nov. 43(11):1970-2. [QxMD MEDLINE Link].

20. Andersson RE, Petzold MG. Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg. 2007 Nov. 246(5):741-8. [QxMD MEDLINE Link].

21. Minneci PC, Mahida JB, Lodwick DL, Sulkowski JP, Nacion KM, Cooper JN, et al. Effectiveness of Patient Choice in Nonoperative vs Surgical Management of Pediatric Uncomplicated Acute Appendicitis. JAMA Surg. 2016 May 1. 151 (5):408-15. [QxMD MEDLINE Link].

22. Bachur RG, Lipsett SC, Monuteaux MC. Outcomes of Nonoperative Management of Uncomplicated Appendicitis. Pediatrics. 2017 Jun 2. [QxMD MEDLINE Link].

23. Emil S, Elkady S, Shbat L, et al. Determinants of postoperative abscess occurrence and percutaneous drainage in children with perforated appendicitis. Pediatr Surg Int. 2014 Dec. 30(12):1265-71. [QxMD MEDLINE Link].

24. Arias-Llorente RP, Florez-Diez P, Oviedo-Gutierrez M, et al. Acute neonatal appendicitis: A diagnosis to consider in abdominal sepsis. J Neonatal Perinatal Med. 2014 Jan 1. 7(3):241-6. [QxMD MEDLINE Link].

25. Nicole M, Desjardins MP, Gravel J. Bedside Sonography Performed by Emergency Physicians to Detect Appendicitis in Children. Acad Emerg Med. 2018 Sep. 25 (9):1035-1041. [QxMD MEDLINE Link].

Adam C Alder, MD Assistant Professor, Department of Surgery, Division of Pediatric Surgery, Children's Medical Center, University of Texas Southwestern Medical Center at Dallas, Southwestern Medical School

Adam C Alder, MD is a member of the following medical societies: American College of Surgeons, Society of American Gastrointestinal and Endoscopic Surgeons, Texas Medical Association, International Pediatric Endosurgery Group

Disclosure: Nothing to disclose.

Robert K Minkes, MD, PhD, MS Professor of Anatomy and Surgery, Founding Faculty, Orlando College of Osteopathic Medicine

Robert K Minkes, MD, PhD, MS is a member of the following medical societies: Alpha Omega Alpha, American College of Surgeons, American Medical Association, American Pediatric Surgical Association, Phi Beta Kappa

Disclosure: Nothing to disclose.

Carmen Cuffari, MD Associate Professor, Department of Pediatrics, Division of Gastroenterology/Nutrition, Johns Hopkins University School of Medicine

Carmen Cuffari, MD is a member of the following medical societies: American College of Gastroenterology, American Gastroenterological Association, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, Royal College of Physicians and Surgeons of Canada

Disclosure: Received honoraria from Prometheus Laboratories for speaking and teaching; Received honoraria from Abbott Nutritionals for speaking and teaching. for: Abbott Nutritional, Abbvie, speakers' bureau.

Kirsten A Bechtel, MD Associate Professor, Department of Pediatrics, Yale University School of Medicine; Attending Physician, Department of Pediatric Emergency Medicine, Yale-New Haven Children's Hospital

Kirsten A Bechtel, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Deborah F Billmire, MD Associate Professor, Department of Surgery, Indiana University Medical Center

Deborah F Billmire, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, Phi Beta Kappa, and Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Jeffrey J DuBois, MD Chief of Children's Surgical Services, Division of Pediatric Surgery, Kaiser Permanente, Women and Children's Center, Roseville Medical Center

Jeffrey J DuBois, MD, is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American College of Surgeons, American Pediatric Surgical Association, and California Medical Association

Disclosure: Nothing to disclose.

Michael Stephen Freitas, MS State University of New York at Buffalo School of Medicine and Biomedical Sciences

Michael Stephen Freitas, MS is a member of the following medical societies: American College of Surgeons, American Medical Association, American Physical Therapy Association, and Medical Society of the State of New York

Disclosure: Nothing to disclose.

Philip Glick, MD, MBA Professor, Departments of Surgery, Pediatrics, and Gynecology and Obstetrics, Vice-Chairperson for Finance and Development, Department of Surgery, State University of New York at Buffalo

Philip Glick, MD, MBA is a member of the following medical societies: Alpha Omega Alpha, American Academy of Pediatrics, American College of Surgeons, American Medical Association, American Pediatric Surgical Association, American Thoracic Society, Association for Academic Surgery, Association for Surgical Education, Central Surgical Association, Federation of American Societies for Experimental Biology, Medical Society of the State of New York, Phi Beta Kappa, Physicians for Social Responsibility, Royal College of Surgeons of England, Sigma Xi, Society for Pediatric Research, Society for Surgery of the Alimentary Tract, Society of Critical Care Medicine, and Society of University Surgeons

Disclosure: Nothing to disclose.

Kara E Hennelly, MD Fellow, Department of Pediatric Emergency Medicine, Children's Hospital Boston

Kara E Hennelly, MD is a member of the following medical societies: American Academy of Pediatrics

Disclosure: Nothing to disclose.

Michael S Katz, MD Research Fellow, Department of Pediatric Surgery, St Christopher's Hospital for Children

Michael S Katz, MD is a member of the following medical societies: American College of Surgeons, American Medical Association, and American Medical Student Association/Foundation

Disclosure: Nothing to disclose.

Robert Kelly, MD Chairman, Department of Surgery, Departments of Surgery and Pediatrics, Children's Hospital of the King's Daughters; Associate Professor, Eastern Virginia Medical School

Robert Kelly, MD is a member of the following medical societies: American Academy of Pediatrics, American College of Surgeons, American Medical Association, American Pediatric Surgical Association, American Society of Abdominal Surgeons, Medical Society of Virginia, Norfolk Academy of Medicine, and Southern Medical Association

Disclosure: Nothing to disclose.

David A Piccoli, MD Chief of Pediatric Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia; Professor, University of Pennsylvania School of Medicine

David A Piccoli, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American Gastroenterological Association, and North American Society for Pediatric Gastroenterology and Nutrition

Disclosure: Nothing to disclose.

Jeffrey R Tucker, MD Assistant Professor, Department of Pediatrics, Division of Emergency Medicine, University of Connecticut School of Medicine, Connecticut Children's Medical Center

Disclosure: Merck Salary Employment

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Wayne Wolfram, MD, MPH Associate Professor, Department of Emergency Medicine, Mercy St Vincent Medical Center

Wayne Wolfram, MD, MPH is a member of the following medical societies: American Academy of Emergency Medicine, American Academy of Pediatrics, and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

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