Cholestasis Questions & Answers

Updated: Aug 09, 2017
  • Author: Hisham Nazer, MBBCh, FRCP, DTM&H; Chief Editor: Carmen Cuffari, MD  more...
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Questions & Answers

Overview

What is cholestasis?

What is the role of xanthomas in the pathophysiology of cholestasis?

What is the pathophysiology of hepatocellular cholestasis?

What is the pathophysiology of obstructive cholestasis?

What is the role of bile salt retention in the pathophysiology of cholestasis?

Why are neonates at higher risk for cholestasis?

What are the primary pathophysiologic effects of cholestasis?

What is the role of conjugated bilirubin retention in the pathophysiology of cholestasis?

What is the role of increased serum concentration in the pathophysiology of cholestasis?

What is the role of hypercholemia in the pathophysiology of cholestasis?

What is the role of pruritus in the pathophysiology of cholestasis?

What is the role of hyperlipidemia in the pathophysiology of cholestasis?

What causes failure to thrive in infants with cholestasis?

What is the mortality and morbidity in cholestasis?

How does the incidence of cholestasis vary by sex?

Which patient groups have the highest incidence of cholestasis?

Presentation

Which clinical history findings are characteristic of cholestasis?

Which physical findings are characteristic of cholestasis?

What are causes of obstructive cholestasis?

What are causes of hepatocellular cholestasis?

Workup

Which lab studies are performed in the workup of cholestasis?

What is the role of imaging studies in the workup of cholestasis?

Which surgical procedures are performed in the workup of cholestasis?

Which histologic findings are characteristic of cholestasis?

Treatment

What are medical treatment options for cholestasis?

When is surgery indicated in the treatment of cholestasis?

Which specialists should be consulted in the treatment of cholestasis?

Which dietary modifications are used in the treatment of cholestasis?

Follow-up

When is inpatient care indicated in the treatment of cholestasis?

Medications

Which medications in the drug class Gastrointestinal Agents, Other are used in the treatment of Cholestasis?

Which medications in the drug class Antibiotics are used in the treatment of Cholestasis?

Which medications in the drug class Bile salt resins are used in the treatment of Cholestasis?

Which medications in the drug class Opioid antagonists are used in the treatment of Cholestasis?

Which medications in the drug class Vitamins are used in the treatment of Cholestasis?

Which medications in the drug class Barbiturates are used in the treatment of Cholestasis?

Which medications in the drug class Choleretic agents are used in the treatment of Cholestasis?