Rotator Cuff Injury Medication

Updated: Oct 25, 2018
  • Author: Gerard A Malanga, MD; Chief Editor: Craig C Young, MD  more...
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Medication

Medication Summary

NSAIDs are frequently used at the onset of rotator cuff injuries to reduce inflammation and control pain. Currently, good clinical studies justifying routine NSAID use are not available. In addition, adverse effect profiles and patient tolerance of NSAIDs may preclude their use in some cases. Various NSAIDs are available over the counter or by prescription. Use proper doses in the acute phase of rotator cuff injuries for a few days to a week, and stop when pain and inflammation begin to subside.

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Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Class Summary

NSAIDs have analgesic and antipyretic activities. The mechanism of action of these agents is not known, but they may inhibit cyclooxygenase (COX) activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell-membrane functions. Treatment of pain tends to be patient specific.

Ibuprofen (Ibuprin, Advil, Motrin)

DOC for mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Ketoprofen (Actron, Orudis)

For the relief of mild to moderate pain and inflammation.

Small dosages are initially indicated in small and elderly patients and in those with renal or liver disease.

Doses >75 mg do not increase therapeutic effects. Administer high doses with caution, and closely observe patient for response.

Naproxen (Naprosyn, Naprelan, Anaprox)

For the relief of mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing activity of COX, which results in a decrease of prostaglandin synthesis.

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