Intestinal Enterokinase Deficiency Treatment & Management

Updated: Nov 28, 2017
  • Author: Agostino Nocerino, MD, PhD; Chief Editor: Carmen Cuffari, MD  more...
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Treatment

Medical Care

Pancreatic enzyme replacement is indicated in patients with intestinal enterokinase deficiency.

In exocrine pancreatic deficiency, the efficacy of enzyme substitution therapy appears to be higher when enzymes are administered either portioned along with meals or just after meals. Administration of enzymes in the form of enteric-coated minimicrospheres avoids acid-mediated lipase inactivation and ensures gastric emptying of enzymes in parallel with nutrients. [9, 10]

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Diet

Treatment of enterokinase deficiency involves no dietetic restrictions or recommendations after starting proper pancreatic enzyme replacement therapy.

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