Pediatric Rectal Prolapse Medication

Updated: Dec 12, 2019
  • Author: Jaime Shalkow, MD, FACS; Chief Editor: Carmen Cuffari, MD  more...
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Medication Summary

There is no specific medical treatment for rectal prolapse, however, management of constipation, treatment of associated parasitic infections, and avoiding excessive strain are appropriate measures for the management of uncomplicated rectal prolapse.

Pancreatic enzyme replacement may be useful on CF patients with rectal prolapse with a 72% efficacy  [1] .


Stool softeners

Class Summary

In addition to dietary modification, stool softeners help to decrease bowel movement straining secondary to constipation.

Polyethylene glycol solution (MiraLAX, Dulcolax Balance)

Polyethylene glycol is an osmotic stool softener used for treatment of occasional constipation. In theory, there is less risk of dehydration or electrolyte imbalance with isotonic polyethylene glycol than with hypertonic sugar solutions. A laxative effect is generated because polyethylene glycol is not absorbed and continues to hold water by osmotic action through the small bowel and colon, resulting in mechanical cleansing.

Polyethylene glycol is supplied with a measuring cap marked to contain 17 g of laxative powder when filled to the indicated line. It may require 2-4 days (48-96 hours) to produce bowel movement.

Mineral oil (Fleet Mineral Oil Enema, Kondremul)

Mineral oil lubricates the intestine and facilitates the passage of stool by decreasing water absorption from the intestine.

Lactulose (Enulose, Generlac, Kristalose, Constulose)

Lactulose is an osmotic agent and ammonium detoxifying agent. It produces an osmotic effect in the colon that results in distention and promotes peristalsis.