Sandifer Syndrome Questions & Answers

Updated: Apr 10, 2020
  • Author: Pegeen Eslami, MD; Chief Editor: Carmen Cuffari, MD  more...
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Questions & Answers

Overview

What is Sandifer syndrome?

What is the pathophysiology of Sandifer syndrome?

What is the incidence of Sandifer syndrome internationally?

What is the mortality and morbidity associated with Sandifer syndrome?

What are the racial predilections of Sandifer syndrome?

What are the sexual predilections of Sandifer syndrome?

Which age group has the highest incidence of Sandifer syndrome?

Presentation

What are the signs and symptoms of Sandifer syndrome?

What are complications in Sandifer syndrome?

Which physical findings are characteristic of Sandifer syndrome?

What causes Sandifer syndrome?

DDX

Which conditions should be included in the differential diagnoses of Sandifer syndrome?

What are the differential diagnoses for Sandifer Syndrome?

Workup

How is Sandifer syndrome diagnosed?

What is the role of lab tests in the workup of Sandifer syndrome?

What is the role of imaging studies in the workup of Sandifer syndrome?

What is the role of video-EEG monitoring in the workup of Sandifer syndrome?

How is the severity of GERD assessed in the workup of Sandifer syndrome?

What is the role of endoscopy in the workup of Sandifer syndrome?

Which histologic findings are characteristic of Sandifer syndrome?

Treatment

What are the treatment options for Sandifer syndrome?

How is Sandifer syndrome treated?

What is the role of surgery in the treatment of Sandifer syndrome?

Which specialist consultations are beneficial for patients with Sandifer syndrome?

What is the role of dietary interventions in the treatment of Sandifer syndrome?

Medications

When is therapeutic response to the treatment of GERD expected in patients with Sandifer syndrome?

Which medications in the drug class Proton pump inhibitors are used in the treatment of Sandifer Syndrome?

Which medications in the drug class H2 receptor antagonists are used in the treatment of Sandifer Syndrome?

Which medications in the drug class Antacids are used in the treatment of Sandifer Syndrome?

Which medications in the drug class Prokinetic agents are used in the treatment of Sandifer Syndrome?