Pediatric Celiac Disease (Sprue) Questions & Answers

Updated: Jul 07, 2023
  • Author: Stefano Guandalini, MD, AGAF; Chief Editor: Carmen Cuffari, MD  more...
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Questions & Answers

Overview

What is pediatric celiac disease?

What is the pathogenesis of pediatric celiac disease?

What is the role of innate immunity in the pathophysiology of pediatric celiac disease?

What is the role of adaptive immunity in the pathophysiology of pediatric celiac disease?

What is the anatomy of small intestine relevant to pediatric celiac disease?

What is the histological classification of pediatric celiac disease?

What is the prevalence of pediatric celiac disease in the US?

What is the global prevalence of pediatric celiac disease?

What is the mortality and morbidity associated with pediatric celiac disease?

What are the racial predilections of pediatric celiac disease?

What are the sexual predilections of pediatric celiac disease?

Which age groups have the highest prevalence of celiac disease?

What is the prognosis of pediatric celiac disease?

What is the role of patient education in the treatment of pediatric celiac disease?

Presentation

What are the types of pediatric celiac disease?

What are the signs and symptoms of typical pediatric celiac disease?

What are the signs and symptoms of atypical pediatric celiac disease?

What are the extraintestinal signs and symptoms of pediatric celiac disease?

Which conditions are associated with pediatric celiac disease?

What are the signs and symptoms of pediatric celiac disease in patients with type 1 diabetes mellitus?

What are the signs and symptoms of pediatric celiac disease in patients with Down syndrome?

What are the possible complications of pediatric celiac disease?

Which physical findings are characteristic of pediatric celiac disease?

What causes pediatric celiac disease?

DDX

What are the differential diagnoses for Pediatric Celiac Disease (Sprue)?

Workup

What is the role of lab tests in the workup of pediatric celiac disease?

What is the role of imaging studies in the workup of pediatric celiac disease?

What is the role of biopsy in the workup of pediatric celiac disease?

Which histologic findings are characteristic of pediatric celiac disease?

Treatment

How is pediatric celiac disease treated?

Which specialist consultations are beneficial for patients with pediatric celiac disease?

Which activity modifications are used in the treatment of pediatric celiac disease?

How are recurrences of celiac disease prevented?

What is included in the long-term monitoring of pediatric celiac disease?

Guidelines

What are the guidelines for the diagnosis and management of celiac disease?

Medications

What is the role of medications in the treatment of pediatric celiac disease?

Which medications in the drug class Glucocorticoids are used in the treatment of Pediatric Celiac Disease (Sprue)?