Atlantoaxial Instability (Atlantoaxial Subluxation) Medication

Updated: May 21, 2021
  • Author: Chris G Koutures, MD, FAAP; Chief Editor: Craig C Young, MD  more...
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Medication Summary

Some authorities and cervical spine trauma protocols recommend the administration of high-dose intravenous steroids in the initial presentation of acute cervical spine injuries. The reasoning is to potentially reduce cervical cord swelling and subsequent neurologic sequelae. This approach is not a uniform treatment recommendation. Otherwise, no medical therapy is indicated for symptomatic or asymptomatic AAI instability.



Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Methylprednisolone (Solu-Medrol, Depo-Medrol, Medrol)

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.