Proteus Syndrome Medication

Updated: Jun 13, 2018
  • Author: Megan E Barry, MD; Chief Editor: Luis O Rohena, MD, PhD, FAAP, FACMG  more...
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Medication Summary

Drug therapy is not currently a component of the standard of care for Proteus syndrome (see Treatment). However, a study by Lindhurst et al indicated that ARQ 092 reduces the abnormally increased phosphorylation of the protein kinase Akt occurring in cells and tissues with the AKT1 E17K Proteus syndrome mutation. This suggests that the agent, which is under investigation as a cancer therapy, may also offer a treatment for Proteus syndrome. [24]