Overview
What is Silver-Russell syndrome (SRS)?
What is the pathophysiology of Silver-Russell syndrome (SRS)?
What is the prevalence of Silver-Russell syndrome (SRS)?
What is the mortality and morbidity associated with Silver-Russell syndrome (SRS)?
What are the sexual predilections of Silver-Russell syndrome (SRS)?
At what age are the clinical features of Silver-Russell syndrome (SRS) most evident?
Presentation
What are the diagnostic criteria for Silver-Russell syndrome (SRS)?
Which dysmorphic findings are characteristic of Silver-Russell syndrome (SRS)?
Which growth and skeletal findings are characteristic of Silver-Russell syndrome (SRS)?
Which genital anomalies are characteristic of Silver-Russell syndrome (SRS)?
Which radiographic findings are characteristic of Silver-Russell syndrome (SRS)?
How frequently are cardiac defects or malignancies associated with Silver-Russell syndrome (SRS)?
What causes Silver-Russell syndrome (SRS)?
DDX
Which conditions are included in the differential diagnoses of Silver-Russell syndrome (SRS)?
What are the differential diagnoses for Silver-Russell Syndrome?
Workup
How is Silver-Russell syndrome (SRS) diagnosed?
What is the role of lab studies in the workup of Silver-Russell syndrome (SRS)?
What is the role of imaging studies in the workup of Silver-Russell syndrome (SRS)?
Treatment
How is Silver-Russell syndrome (SRS) treated?
What is the role of surgery in the treatment of Silver-Russell syndrome (SRS)?
Which specialist consultations are beneficial to patients with Silver-Russell syndrome (SRS)?
Which dietary modifications are used in the treatment of Silver-Russell syndrome (SRS)?
Guidelines
What are the guidelines for the diagnosis and treatment of Silver-Russell syndrome (SRS)?
Medications
Which medications are used in the treatment of Silver-Russell syndrome (SRS) treatment?
Follow-up
When is inpatient care indicated for the treatment of Silver-Russell syndrome (SRS)?
What is the prognosis of Silver-Russell syndrome (SRS)?
What is included in patient education about Silver-Russell syndrome (SRS)?
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Failure of growth in weight, length, and head circumference starting at birth, suggesting an organic etiology that occurred in utero.