van der Woude Syndrome Treatment & Management

Updated: Apr 13, 2015
  • Author: Gregory P Conners, MD, MPH, MBA; Chief Editor: Luis O Rohena, MD, FAAP, FACMG  more...
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Treatment

Medical Care

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  • Along with a thorough orofacial examination, a thorough general physical examination helps to determine if other associated anomalies of the cardiovascular system, genitourinary system, limbs, or other organ systems are present.
  • Examination and genetic counseling by a pediatric geneticist (dysmorphologist) is suggested for families that may be affected by van der Woude syndrome. This should include an examination of as many potentially affected family members as possible.
  • The American Academy of Pediatric Dentistry have released guidelines for the treatment of persons with special health care needs. [8]
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Surgical Care

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  • Surgical repair of cleft lip and cleft palate or other anomalies may be required.
  • Reconstruction of the lower lip may involve dermal allograft reconstruction. [9]
  • Even in less severely affected individuals, surgical excision of lip pits is often performed, either to alleviate discomfort or for cosmetic reasons (eg, improving the appearance of lip pits or reducing mucous discharge). Surgical removal of salivary tracts associated with lip pits may be challenging because they may be quite long, extending into other oral structures. [10]
  • Infectious complications of cleft repairs are reportedly more common in patients with van der Woude syndrome than with other children undergoing similar surgery. [11]
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Consultations

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  • Treatment of children with cleft palate is often best undertaken by a multidisciplinary team of pediatric plastic surgeons; dentists; otolaryngologists; geneticists; genetic counselors; social workers; and occupational, speech, and physical therapists.
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