Overview
What is pediatric chronic granulomatous disease (CGD)?
What are the signs and symptoms of pediatric chronic granulomatous disease (CGD)?
How is pediatric chronic granulomatous disease (CGD) diagnosed?
What is included in the management of pediatric chronic granulomatous disease (CGD)?
What is the pathophysiology of pediatric chronic granulomatous disease (CGD)?
What is the US prevalence of pediatric chronic granulomatous disease (CGD)?
What is the global prevalence of pediatric chronic granulomatous disease (CGD)?
What is the morbidity and mortality associated with pediatric chronic granulomatous disease (CGD)?
What are the racial predilections of pediatric chronic granulomatous disease (CGD)?
What are the sexual predilections of pediatric chronic granulomatous disease (CGD)?
At what age is pediatric chronic granulomatous disease (CGD) typically diagnosed?
Presentation
Which clinical history findings are characteristic of pediatric chronic granulomatous disease (CGD)?
Which physical findings are characteristic of pediatric chronic granulomatous disease (CGD)?
DDX
What are the differential diagnoses for Pediatric Chronic Granulomatous Disease?
Workup
What is the role of genetic testing in the workup of pediatric chronic granulomatous disease (CGD)?
How is pediatric chronic granulomatous disease (CGD) diagnosed prenatally?
Which lab findings are characteristic of pediatric chronic granulomatous disease (CGD)?
What is the role of imaging studies in the workup of pediatric chronic granulomatous disease (CGD)?
Which histologic findings are characteristic of pediatric chronic granulomatous disease (CGD)?
Treatment
How is pediatric chronic granulomatous disease (CGD) treated?
How are active infections treated in pediatric chronic granulomatous disease (CGD)?
How is WBC function improved in patients with pediatric chronic granulomatous disease (CGD)?
What is the role of HSCT in the treatment of pediatric chronic granulomatous disease (CGD)?
What is the role of gene therapy in the treatment of pediatric chronic granulomatous disease (CGD)?
What is the role of surgery in the treatment of pediatric chronic granulomatous disease (CGD)?
Follow-up
What are the possible complications of pediatric chronic granulomatous disease (CGD)?
What is the prognosis of pediatric chronic granulomatous disease (CGD)?
Medications
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Scanning electron micrograph of Aspergillus species.