Pediatric Thrombocytosis Follow-up

Updated: Aug 17, 2020
  • Author: Susumu Inoue, MD; Chief Editor: Hassan M Yaish, MD  more...
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In primary thrombocytosis, thrombosis and/or hemorrhage may occur. In reactive thrombocytosis, an excessively high platelet count combined with other risk factor (eg, vasculitis) or a separate thrombophilic factor (eg, heterozygous protein C deficiency) may increase the risk of thrombosis and/or hemorrhage. However, the risk of this type of complications can be regarded as being extremely small.



Reactive or secondary thrombocytosis is self-limited and transient. However, in certain situations, it may persist. These situations include postsplenectomy thrombocytosis, thrombocytosis associated with chronic hemolytic disease, and thrombocytosis associated with vasculitis and/or connective tissue disorder and/or chronic inflammation.

The prognosis of children with essential thrombocytosis (ET) appears no different from that of adults. Adult patients have near-normal life expectancy because of the low rate of leukemic conversion. However, no child has been monitored long enough for that statement to be applicable to children. The major morbidity factor is the increased risk of thrombohemorrhagic complications.


Patient Education

For reactive thrombocytosis, assuring the patient that the disease is self-limited and harmless is the only patient education required.

For excellent patient education resources, visit eMedicineHealth's Skin Conditions and Beauty Center. Also, see eMedicineHealth's patient education article Bruises.