Overview
What is pediatric von Willebrand disease (VWD)?
What is the pathophysiology of pediatric von Willebrand disease (VWD)?
What is the pathophysiology of type 3 pediatric von Willebrand disease (VWD)?
What is the pathophysiology of type 1 pediatric von Willebrand disease (VWD)?
What is the pathophysiology of type 2 pediatric von Willebrand disease (VWD)?
What is the prevalence of pediatric von Willebrand disease (VWD) in the US?
What is the global prevalence of pediatric von Willebrand disease (VWD)?
What is the mortality and morbidity associated with pediatric von Willebrand disease (VWD)?
What are the racial predilections of pediatric von Willebrand disease (VWD)?
What are the sexual predilections of pediatric von Willebrand disease (VWD)?
At what age is pediatric von Willebrand disease (VWD) diagnosed?
Presentation
How is pediatric von Willebrand disease (VWD) diagnosed?
Which clinical history findings are characteristic of pediatric von Willebrand disease (VWD)?
Which physical findings are characteristic of pediatric von Willebrand disease (VWD)?
What causes pediatric von Willebrand disease (VWD)?
What conditions are associated with acquired pediatric von Willebrand disease (VWD)?
DDX
What are the differential diagnoses for Pediatric Von Willebrand Disease?
Workup
Which tests are used to screen for pediatric von Willebrand disease (VWD)?
Which specific assays are performed in the workup of pediatric von Willebrand disease (VWD)?
What is the role of CBC count in the screening of pediatric von Willebrand disease (VWD)?
What is the role of multimer analysis in the workup of pediatric von Willebrand disease (VWD)?
What are the ACOG guidelines for the evaluation of pediatric von Willebrand disease (VWD)?
What is the role of genetic analysis in the workup of pediatric von Willebrand disease (VWD)?
Treatment
How is pediatric von Willebrand disease (VWD) treated?
Which activity modifications are used in the treatment of pediatric von Willebrand disease (VWD)?
Follow-up
Which medications should be avoided by patients with pediatric von Willebrand disease (VWD)?
What is the prognosis of pediatric von Willebrand disease (VWD)?
What is included in patient education about pediatric von Willebrand disease (VWD)?
Medications
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Structure and domains of von Willebrand factor.