Pediatric Factor XIII Deficiency Questions & Answers

Updated: Mar 15, 2019
  • Author: Helge Dirk Hartung, MD; Chief Editor: Cameron K Tebbi, MD  more...
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Questions & Answers

Overview

What is pediatric factor XIII (FXIII) deficiency?

What is the pathophysiology of pediatric factor XIII (FXIII) deficiency?

What is the prevalence of pediatric factor XIII (FXIII) deficiency?

What is the morbidity and mortality associated with pediatric factor XIII (FXIII) deficiency?

What are the sexual predilections of pediatric factor XIII (FXIII) deficiency?

At what age is the diagnosis of pediatric factor XIII (FXIII) deficiency typically made?

Presentation

Which clinical history findings are characteristic of pediatric factor XIII (FXIII) deficiency?

Which physical findings are characteristic of pediatric factor XIII (FXIII) deficiency?

DDX

Which conditions are included in the differential diagnoses of pediatric factor XIII (FXIII) deficiency?

Workup

Which tests are performed to screen for pediatric factor XIII (FXIII) deficiency?

What is the role of functional assays in the workup of pediatric factor XIII (FXIII) deficiency?

What is the role of immunologic assays in the workup of pediatric factor XIII (FXIII) deficiency?

What is the role of imaging studies in the workup of pediatric factor XIII (FXIII) deficiency?

Treatment

How is pediatric factor XIII (FXIII) deficiency treated?

How are patients with pediatric factor XIII (FXIII) deficiency undergoing surgical procedures managed?

Which specialist consultations are beneficial to patients with pediatric factor XIII (FXIII) deficiency?

Medications

What is the role of clotting factors in the treatment of pediatric factor XIII (FXIII) deficiency?

Follow-up

Which specialists should provide long-term monitoring of pediatric factor XIII (FXIII) deficiency?

What is the role of prophylaxis in the treatment of pediatric factor XIII (FXIII) deficiency?

What is included in patient education about pediatric factor XIII (FXIII) deficiency?