Pediatric Botulism Differential Diagnoses

Updated: Feb 23, 2018
  • Author: Muhammad Waseem, MBBS, MS, FAAP, FACEP, FAHA; Chief Editor: Russell W Steele, MD  more...
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DDx

Diagnostic Considerations

Guillain-Barré syndrome (especially Miller-Fisher variant)

Acute poliomyelitis

Myasthenia gravis

Lambert-Eaton syndrome

Tick paralysis

Stroke

Aminoglycoside toxicity

Atropine poisoning

Paralytic shellfish poisoning (saxitoxin)

Puffer fish ingestion (tetrodotoxin)

Sepsis

Meningitis/encephalitis

Congenital myopathy

Electrolyte imbalance

Genetic metabolic disorders

In infants, it is especially important to consider the diagnoses of sepsis, CNS infections, electrolyte disorders, dehydration, inborn errors of metabolism, spinal muscular atrophy, infantile myasthenia gravis, muscular dystrophy and hypothyroidism. [25]

Differential Diagnoses