Pediatric Herpes Simplex Virus Infection Questions & Answers

Updated: Feb 27, 2019
  • Author: J Michael Klatte, MD; Chief Editor: Russell W Steele, MD  more...
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Questions & Answers

Overview

How are herpes simplex virus (HSV) infections transmitted?

What are the clinical presentations of herpes simplex virus (HSV)?

What are the signs and symptoms of orolabial herpes simplex virus (HSV) infection?

What are the signs and symptoms of genital herpes simplex virus (HSV) infection?

How is herpes neonatorum categorized?

What are the signs and symptoms of herpes simplex virus (HSV) infection of the CNS?

How is herpes simplex virus (HSV) infection diagnosed in children?

Which antiviral agents are used for the treatment of herpes simplex virus (HSV) in neonates?

What are the indications for inpatient management of pediatric herpes simplex virus (HSV) infections?

How is transmission of genital herpes simplex virus (HSV) infection prevented?

How is transmission of herpes simplex virus (HSV) to newborns prevented?

What is herpes simplex virus (HSV)?

What is the pathophysiology of herpes simplex virus (HSV) infection?

What is the prevalence of herpes simplex virus (HSV) in the US?

What is the global prevalence of herpes simplex virus (HSV)?

What causes mortality in herpes simplex virus (HSV) infections?

What is the risk of herpes simplex virus (HSV) transmission from a mother to her infant?

What is the incidence of neonatal herpes simplex virus (HSV) infection?

What are the racial predilections of herpes simplex virus (HSV) infection?

How does the incidence of herpes simplex virus (HSV) vary by sex?

How does the prevalence of herpes simplex virus (HSV) infection vary by age?

Presentation

What is the clinical presentation of herpes simplex virus (HSV) infection?

What is the common clinical presentation of primary orolabial herpes simplex virus (HSV) infection?

What are the signs and symptoms of primary orolabial herpes simplex virus (HSV) infection?

What are the signs and symptoms of reactivation of orolabial herpes simplex virus (HSV) infection?

What is the presentation of primary genital herpes simplex virus (HSV) infections?

What is are the signs and symptoms of reactivation of genital herpes simplex virus (HSV) infections?

Why is the rate of intrauterine and perinatal herpes simplex virus (HSV) infection highest in neonates exposed to primary maternal infections?

How is herpes neonatorum categorized?

What are the signs and symptoms of herpes simplex virus (HSV) infection of the CNS?

What is the presentation of herpes simplex virus (HSV) infection in immunocompromised patients?

What are less common manifestations of herpes simplex virus (HSV) infections?

Which physical findings are characteristic of neonatal herpes simplex virus (HSV) infections?

Which physical findings are characteristic of orolabial herpes simplex virus (HSV) infections?

Which physical findings are characteristic of genital herpes simplex virus (HSV) infections?

Which physical findings are characteristic of herpes simplex virus (HSV) infections of the CNS?

Which physical findings are characteristic of herpes simplex virus (HSV) infection in the immunocompromised patient?

Which physical findings are characteristic of ocular herpes simplex virus (HSV) infections?

DDX

What are the differential diagnoses for Pediatric Herpes Simplex Virus Infection?

Workup

What is the preferred method for diagnosis of herpes simplex virus (HSV) infections?

What is the role of skin scrapings in the workup of herpes simplex virus (HSV)?

What is the role of Tzanck preparation in the workup of herpes simplex virus (HSV) infections?

What is the role of serologic diagnosis in the management of herpes simplex virus (HSV)?

What is the role of cerebrospinal fluid (CSF) analysis in the evaluation of herpes simplex virus (HSV)?

What is the role of PCR in the workup of herpes simplex virus (HSV) infections?

What is the role of immunofluorescent microscopy in the workup of herpes simplex virus (HSV) infection?

Which CSF findings suggest Mollaret meningitis in herpes simplex virus (HSV) infection?

What is the role of imaging studies in the workup of herpes simplex virus (HSV) infections?

What is the role of electroencephalography in the workup of herpes simplex virus (HSV) infection?

Which procedures may be helpful in the diagnosis of herpes simplex virus (HSV) infection?

Which histologic findings are characteristic of herpes simplex virus (HSV) infection?

Treatment

What are medical care options for herpes simplex virus (HSV) infection?

Which specialist consultations may be needed for the treatment of herpes simplex virus (HSV)?

Guidelines

What are the American Academy of Pediatrics (AAP) guidelines for the evaluation of asymptomatic neonates exposed to herpes simplex virus (HSV) during delivery?

Medications

Which antiviral agents are used in the treatment of herpes simplex virus (HSV) infections?

Which medications in the drug class Antiviral agents are used in the treatment of Pediatric Herpes Simplex Virus Infection?

Follow-up

What is included in long-term monitoring of pediatric herpes simplex virus (HSV) infection?

When is inpatient management indicated for herpes simplex virus (HSV) infections?

How is recurrent herpes simplex virus (HSV) infection treated?

What is the indication for transfer in herpes simplex virus (HSV) infections?

How is genital herpes simplex virus (HSV) infection prevented?

How is transmission of herpes simplex virus (HSV) from mother to infant prevented?

What are complications of herpes simplex virus (HSV) infection?

What is the prognosis of herpes simplex virus (HSV) infections?

What should be included in patient education for herpes simplex virus (HSV) infections?