Kawasaki Disease Questions & Answers

Updated: Jul 29, 2018
  • Author: Tina K Sosa, MD; Chief Editor: Russell W Steele, MD  more...
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Questions & Answers

Overview

What are the diagnostic features of Kawasaki disease?

What is Kawasaki disease?

What is FEBRILE in regard to Kawasaki disease?

What is incomplete Kawasaki disease?

What is the role of echocardiography in the evaluation of Kawasaki disease?

What are the treatment goals in Kawasaki disease?

Which agents are used as adjunctive medications in the treatment of disease?

What are the treatment guidelines for Kawasaki disease?

When and where was Kawasaki disease first described?

What is the pathophysiology of Kawasaki disease?

What causes Kawasaki disease?

Which features of Kawasaki disease suggest an infectious etiology?

What are the infectious causes of Kawasaki disease?

How is microscopy used to determine the etiology of Kawasaki disease?

Does Kawasaki disease have a genetic predilection?

Which genetic variants are factors in the etiology of Kawasaki disease?

What is the international incidence of Kawasaki disease?

Does Kawasaki disease (KD) have a racial predilection?

Is Kawasaki disease more common in males or females?

How common is Kawasaki disease in the US?

Which age groups have the highest incidence of Kawasaki disease?

What are the cardiovascular complications of Kawasaki disease?

What are the risk factors for coronary artery aneurysm (CAA) in Kawasaki disease?

What is the prognosis of Kawasaki disease?

What information about Kawasaki disease should be provided to patients and their families/caregivers?

Presentation

What are the principal clinical features of Kawasaki disease?

What are the stages of Kawasaki disease?

What is the clinical presentation of the acute febrile stage of Kawasaki disease?

What is the clinical presentation of the subacute stage of Kawasaki disease?

What is the clinical presentation of the convalescent stage of Kawasaki disease?

What is the clinical presentation of chronic Kawasaki disease?

What are the physical exam findings in Kawasaki disease?

DDX

Which infections can mimic Kawasaki disease?

What is the role of respiratory viruses in the pathogenesis of Kawasaki disease?

Why is the prompt diagnosis of Kawasaki disease essential to a good outcome?

What are the differential diagnoses for Kawasaki Disease?

Workup

What are the approach considerations in the workup of Kawasaki disease?

How is cardiac status evaluated in the workup of Kawasaki disease?

Which imaging studies are indicated in the workup of Kawasaki disease?

Which procedures are indicated in the workup of Kawasaki disease?

Which lab studies are indicated when the clinical picture suggests incomplete Kawasaki disease?

What are the indications for additional lab studies in the workup of incomplete Kawasaki disease?

What are the diagnostic criteria for incomplete Kawasaki disease?

What are the indications for treatment of Kawasaki disease in patients with prolonged fever?

What is the role of echocardiography in the workup of Kawasaki disease?

What are the echocardiography findings in the workup of Kawasaki disease?

What is the role of MRA and CTA in the workup of Kawasaki disease?

What is the role of biopsy in the workup of Kawasaki disease?

What are the histologic findings in Kawasaki disease?

How are coronary microvascular lesions characterized in Kawasaki disease?

Treatment

What is the goal of treatment for Kawasaki disease?

What is the role of IV immunoglobulin (IVIG) in the treatment of Kawasaki disease?

How is IV immunoglobulin (IVIG)-resistant Kawasaki disease treated?

What is the role of aspirin in the treatment of Kawasaki disease?

What is the role of corticosteroids in the treatment of Kawasaki disease?

Which adjunctive medications are used in the treatment of Kawasaki disease?

What clinical trials have been done on adjunctive agents for the treatment of Kawasaki disease?

Which specialist consultations are indicated in the treatment of Kawasaki disease?

What is the long-term monitoring for patients with Kawasaki disease?

Guidelines

What are the treatment guidelines for Kawasaki disease?

Medications

Which medications in the drug class Antiplatelet Agents, Cardiovascular are used in the treatment of Kawasaki Disease?

Which medications in the drug class Immunosuppressants are used in the treatment of Kawasaki Disease?

Which medications in the drug class Corticosteroids are used in the treatment of Kawasaki Disease?

Which medications in the drug class Antiplatelet Agents, Hematologic are used in the treatment of Kawasaki Disease?

Which medications in the drug class Nonsteroidal Anti-Inflammatory Agents/Salicylates (NSAIDs) are used in the treatment of Kawasaki Disease?

Which medications in the drug class Immunomodulatory agents are used in the treatment of Kawasaki Disease?