Overview
What is causing an increase in the incidence of measles in the US?
What was the underlying cause of the 2014 outbreak of measles in California?
What were is included in the updated American Academy of Pediatrics measles guidelines?
How is immunity to measles determined?
What is the role of immune globulin in the management of measles?
How is measles exposure managed?
How is measles prevented in patients with HIV infection?
How is measles prevented in healthcare workers?
What are the signs and symptoms of measles?
What are the manifestations of enanthem in measles?
How is rash characterized in measles?
What is the clinical course of measles?
What are the signs and symptoms of modified measles?
What are the signs and symptoms of atypical measles?
How is a diagnosis of measles confirmed?
What is the role of IgM titers in the diagnosis of measles?
What is the role of IgG titers in the diagnosis of measles?
What is the role of viral cultures in the diagnosis of measles?
How is polymerase chain reaction used in the diagnosis of measles?
What is included in measles case reporting?
What is included in supportive care of measles?
What is the role of postexposure prophylaxis in the management of measles?
How is vitamin A supplementation used in the management of measles?
What are possible complications of acute measles?
How many deaths are caused by measles each year?
How effective is the measles vaccine?
Why is a second dose of measles vaccine recommended?
What has contributed to a resurgence of measles?
What tissues does the measles virus infect?
What are the features of immunosuppression caused by measles?
What is the progression of measles in individuals with deficiencies in cellular immunity?
What is the response to measles in immunocompetent individuals?
What are the risk factors for measles virus infection?
What are the risk factors for severe measles?
What was the reason for implementing 2 doses of live-attenuated measles vaccine?
What was the magnitude of the resurgence of measles from 1989 to 1991?
What is the cause of most cases of measles in the US?
What was the incidence of measles between 2000 and 2007?
What was the incidence of measles in 2008?
What is the highest reported number of measles cases since 1996?
What is the prevalence of measles in the US?
What is the impact of measles in developing countries?
What was the global incidence of measles at the end of the 20th century?
What is the global incidence of measles?
What age group is at the highest risk for measles?
How does the incidence of measles vary by age?
What is the most common age group affected by measles in developing countries?
How does the incidence of measles vary by sex?
What are the racial predilections of measles?
What is the prognosis of measles in the US?
How many deaths are caused by measles globally?
What age group is at highest risk for-fatality from measles?
Which age groups are at highest risk for complications of measles?
What are the most common causes of death associated with measles?
Presentation
What is the incubation period for measles?
What are the initial symptoms of measles?
How is enanthem characterized in measles?
What is the course of uncomplicated measles?
What is the disease course of modified measles?
What are the physical findings of enanthem in measles?
What are the physical findings characteristic of exanthem in measles?
What causes complications in measles?
Which patients are at highest risk for complications of measles?
What are common infectious complications of measles?
What are rare infectious complications of measles?
What is the incidence of encephalitis as a complication of measles?
What is the incidence of SSPE as a complication of measles?
What are the complications of measles during pregnancy?
DDX
What are the signs and symptoms of atypical measles?
What is the pathogenesis of atypical measles?
Which conditions should be included in the differential diagnoses of measles?
What are the differential diagnoses for Measles?
Workup
What is the role of lab studies in the diagnosis of measles?
Why is case reporting of measles required?
How does the CDC classify cases of measles?
What is the role of IgM antibody assays in the workup of measles?
How long do measles serum IgM level remains positive?
What is the role of IgG antibody assays in the diagnosis of measles?
When should specimens be drawn for an IgG antibody assay in the workup of measles?
What are the considerations of IgG testing for individuals with atypical measles?
What do IgG levels indicate in the workup of measles?
What is the role of viral culture in the workup of measles?
What is the role of viral genotyping in the workup of measles?
Medications
Which medications in the drug class Immunoglobulins are used in the treatment of Measles?
Which medications in the drug class Vaccines are used in the treatment of Measles?
Which medications in the drug class Antivirals are used in the treatment of Measles?
Which medications in the drug class Vitamins are used in the treatment of Measles?
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Koplik spots in measles. Photograph courtesy of World Health Organization.
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Enanthem of measles (Koplik spots).
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Measles conjunctivitis.
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Face of boy with measles.
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Morbilliform rash.