Vital Signs. Centers for Disease Control and Prevention. Available at http://www.cdc.gov/vitalsigns/sepsis/. August 23, 2016; Accessed: August 24, 2016.
Brooks M. CDC Puts Spotlight on Sepsis as 'Medical Emergency'. Medscape Medical News. Available at http://www.medscape.com/viewarticle/867826. August 23, 2016; Accessed: August 24, 2016.
Goldstein B, Giroir B, Randolph A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med. 2005 Jan. 6(1):2-8. [QxMD MEDLINE Link].
Gaines NN, Patel B, Williams EA, Cruz AT. Etiologies of septic shock in a pediatric emergency department population. Pediatr Infect Dis J. 2012 Nov. 31(11):1203-5. [QxMD MEDLINE Link].
Soeorg H, Huik K, Parm U, Ilmoja ML, Metelskaja N, Metsvaht T. Genetic Relatedness of Coagulase-negative Staphylococci From Gastrointestinal Tract and Blood of Preterm Neonates With Late-onset Sepsis. Pediatr Infect Dis J. 2013 Apr. 32(4):389-93. [QxMD MEDLINE Link].
Greenhow TL, Hung YY, Herz AM. Changing epidemiology of bacteremia in infants aged 1 week to 3 months. Pediatrics. 2012 Mar. 129(3):e590-6. [QxMD MEDLINE Link].
Harding H. Catheter dwell time longer than two weeks tied to higher sepsis risk in infants. Medscape Medical News. November 12, 2013. Available at http://www.medscape.com/viewarticle/814211. Accessed: November 19, 2013.
Milstone AM, Reich NG, Advani S, Yuan G, Bryant K, Coffin SE, et al. Catheter Dwell Time and CLABSIs in Neonates With PICCs: A Multicenter Cohort Study. Pediatrics. 2013 Nov 11. [QxMD MEDLINE Link].
Stoll BJ, Hansen NI, Bell EF, et al. Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012. JAMA. 2015 Sep 8. 314 (10):1039-51. [QxMD MEDLINE Link].
McMullan BJ, Bowen A, Blyth CC, Van Hal S, Korman TM, Buttery J, et al. Epidemiology and Mortality of Staphylococcus aureus Bacteremia in Australian and New Zealand Children. JAMA Pediatr. 2016 Aug 15. [QxMD MEDLINE Link].
Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011 Jun 30. 364(26):2483-95. [QxMD MEDLINE Link].
Myburgh JA. Fluid resuscitation in acute illness--time to reappraise the basics. N Engl J Med. 2011 Jun 30. 364(26):2543-4. [QxMD MEDLINE Link].
Mitchell HK, Reddy A, Montoya-Williams D, Harhay M, Fowler JC, Yehya N. Hospital outcomes for children with severe sepsis in the USA by race or ethnicity and insurance status: a population-based, retrospective cohort study. Lancet Child Adolesc Health. 2021 Feb. 5 (2):103-12. [QxMD MEDLINE Link].
Mancini N, Carletti S, Ghidoli N, Cichero P, Burioni R, Clementi M. The era of molecular and other non-culture-based methods in diagnosis of sepsis. Clin Microbiol Rev. 2010 Jan. 23(1):235-51. [QxMD MEDLINE Link]. [Full Text].
Rajani AK, Philip AGS. Diagnostic Tests in Neonatology: Evaluation and Interpretation Using Sepsis as an Example. NeoReviews. 2011 Jul. 12(7):e368-e373.
Reinhart K, Bauer M, Riedemann NC, Hartog CS. New approaches to sepsis: molecular diagnostics and biomarkers. Clin Microbiol Rev. 2012 Oct. 25(4):609-34. [QxMD MEDLINE Link].
Mickiewicz B, Thompson GC, Blackwood J, Jenne CN, Winston BW, Vogel HJ, et al. Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis. Crit Care. 2015 Sep 9. 19:320. [QxMD MEDLINE Link].
Reuters. Presepsin an accurate biomarker for late-onset sepsis in preemies. Medscape Medical News. December 18, 2014. [Full Text].
Poggi C, Bianconi T, Gozzini E, Generoso M, Dani C. Presepsin for the Detection of Late-Onset Sepsis in Preterm Newborns. Pediatrics. 2014 Dec 15. [QxMD MEDLINE Link].
Balamuth F, Alpern ER, Abbadessa MK, Hayes K, Schast A, Lavelle J, et al. Improving Recognition of Pediatric Severe Sepsis in the Emergency Department: Contributions of a Vital Sign-Based Electronic Alert and Bedside Clinician Identification. Ann Emerg Med. 2017 Jun 2. [QxMD MEDLINE Link].
Scott HF, Brou L, Deakyne SJ, Kempe A, Fairclough DL, Bajaj L. Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children. JAMA Pediatr. 2017 Mar 1. 171 (3):249-255. [QxMD MEDLINE Link].
[Guideline] Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med. 2008 Jan. 34(1):17-60. [QxMD MEDLINE Link]. [Full Text].
[Guideline] Yager P, Noviski N. Shock. Pediatr Rev. 2010 Aug. 31(8):311-8; quiz 319. [QxMD MEDLINE Link].
Larsen GY, Mecham N, Greenberg R. An emergency department septic shock protocol and care guideline for children initiated at triage. Pediatrics. 2011 Jun. 127(6):e1585-92. [QxMD MEDLINE Link].
Escobar GJ, Puopolo KM, Wi S, Turk BJ, Kuzniewicz MW, Walsh EM, et al. Stratification of Risk of Early-Onset Sepsis in Newborns >=34 Weeks' Gestation. Pediatrics. 2013 Dec 23. [QxMD MEDLINE Link].
Henderson D. Risk-Based EOS Approach Could Curb Antibiotics for Newborns. Medscape [serial online]. Available at http://www.medscape.com/viewarticle/818221. Accessed: December 30, 2013.
Nzegwu NI, Rychalsky MR, Nallu LA, Song X, Deng Y, Natusch AM, et al. Implementation of an Antimicrobial Stewardship Program in a Neonatal Intensive Care Unit. Infect Control Hosp Epidemiol. 2017 Jul 26. 1-7. [QxMD MEDLINE Link].
Evans IVR, Phillips GS, Alpern ER, Angus DC, Friedrich ME, Kissoon N, et al. Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis. JAMA. 2018 Jul 24. 320 (4):358-367. [QxMD MEDLINE Link].
Skinner SC, Iocono JA, Ballard HO, Turner MD, Ward AN, Davenport DL, et al. Improved survival in venovenous vs venoarterial extracorporeal membrane oxygenation for pediatric noncardiac sepsis patients: a study of the Extracorporeal Life Support Organization registry. J Pediatr Surg. 2012 Jan. 47(1):63-7. [QxMD MEDLINE Link].
Rodríguez-Núñez A, López-Herce J, Gil-Antón J, Hernández A, Rey C. Rescue treatment with terlipressin in children with refractory septic shock: a clinical study. Crit Care. 2006 Feb. 10(1):R20. [QxMD MEDLINE Link]. [Full Text].
Manzoni P, Rinaldi M, Cattani S, Pugni L, Romeo MG, Messner H, et al. Bovine lactoferrin supplementation for prevention of late-onset sepsis in very low-birth-weight neonates: a randomized trial. JAMA. 2009 Oct 7. 302(13):1421-8. [QxMD MEDLINE Link].
Pammi M, Abrams SA. Oral lactoferrin for the prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev. 2011 Oct 5. CD007137. [QxMD MEDLINE Link].
Manzoni P, Stolfi I, Messner H, Cattani S, Laforgia N, Romeo MG, et al. Bovine lactoferrin prevents invasive fungal infections in very low birth weight infants: a randomized controlled trial. Pediatrics. 2012 Jan. 129(1):116-23. [QxMD MEDLINE Link].
Haque KN, Pammi M. Pentoxifylline for treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev. 2011 Oct 5. CD004205. [QxMD MEDLINE Link].
Panigrahi P, Parida S, Nanda NC, Satpathy R, Pradhan L, Chandel DS, et al. A randomized synbiotic trial to prevent sepsis among infants in rural India. Nature. 2017 Aug 16. [QxMD MEDLINE Link].
FDA Safety Alert. Xigris [drotrecogin alfa (activated)]: Market Withdrawal - Failure to Show Survival Benefit. US Food and Drug Administration. Available at http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm277143.htm. Accessed: October 26, 2011.
PR Newswire. Lilly Announces Withdrawal of Xigris® Following Recent Clinical Trial Results. Lilly. Available at https://investor.lilly.com/releasedetail2.cfm?ReleaseID=617602. Accessed: October 26, 2011.
Barton P, Kalil AC, Nadel S, Goldstein B, Okhuysen-Cawley R, Brilli RJ, et al. Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis. Pediatrics. 2004 Jan. 113(1 Pt 1):7-17. [QxMD MEDLINE Link].
Weiss KD. Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis. Pediatrics. 2004 Jan. 113(1 Pt 1):134. [QxMD MEDLINE Link].
Japanese Association for Infectious Diseases/Japanese Society of Chemotherapy, The JAID/JSC Guide/Guidelines to Clinical Management of Infectious Disease Preparing Committee, Sepsis working group, Arakawa S, Kasai M, Kawai S, et al. The JAID/JSC guidelines for management of infectious diseases 2017 - Sepsis and catheter-related bloodstream infection. J Infect Chemother. 2021 May. 27 (5):657-77. [QxMD MEDLINE Link]. [Full Text].