Atypical Mycobacterial Infection Differential Diagnoses

1. Masson AM, Prissick FH. Cervical lymphadenitis in children caused by chromogenic Mycobacteria. Can Med Assoc J. 1956 Nov 15. 75(10):798-803. [QxMD MEDLINE Link].

2. Weed LA, Keith HM, Needham GM. Nontuberculous acid-fast cervical adenitis in children. Mayo Clin Proc. 1956 Apr 18. 31(8):259-63. [QxMD MEDLINE Link].

3. Wolinsky E. Nontuberculous mycobacteria and associated diseases. Am Rev Respir Dis. 1979 Jan. 119(1):107-59. [QxMD MEDLINE Link].

4. Silcox VA, Good RC, Floyd MM. Identification of clinically significant Mycobacterium fortuitum complex isolates. J Clin Microbiol. 1981 Dec. 14(6):686-91. [QxMD MEDLINE Link].

5. Wallace RJ, Brown BA, Silcox VA, et al. Clinical disease, drug susceptibility, and biochemical patterns of the unnamed third biovariant complex of Mycobacterium fortuitum. J Infect Dis. 1991 Mar. 163(3):598-603. [QxMD MEDLINE Link].

6. Wallace RJ, Silcox VA, Tsukamura M, et al. Clinical significance, biochemical features, and susceptibility patterns of sporadic isolates of the Mycobacterium chelonae-like organism. J Clin Microbiol. 1993 Dec. 31(12):3231-9. [QxMD MEDLINE Link].

7. Cross JT, Jacobs R. Other mycobacteria. Fegin, Cherry, eds. Textbook of Pediatric Infectious Diseases. Philadelphia, Pa: WB Saunders Co; 1998.

8. Karne SS, Sangle SA, Kiyawat DS, Dharmashale SN, Kadam DB, Bhardwaj RS. Mycobacterium avium-intracellulare brain abscess in HIV-positive patient. Ann Indian Acad Neurol. 2012 Jan. 15(1):54-5. [QxMD MEDLINE Link]. [Full Text].

9. Shiratsuchi H, Johnson JL, Ellner JJ. Bidirectional effects of cytokines on the growth of Mycobacterium avium within human monocytes. J Immunol. 1991 May 1. 146(9):3165-70. [QxMD MEDLINE Link].

10. Denis M, Gregg EO. Recombinant tumour necrosis factor-alpha decreases whereas recombinant interleukin-6 increases growth of a virulent strain of Mycobacterium avium in human macrophages. Immunology. 1990 Sep. 71(1):139-41. [QxMD MEDLINE Link].

11. Bermudez LE, Wu M, Petrofsky M, Young LS. Interleukin-6 antagonizes tumor necrosis factor-mediated mycobacteriostatic and mycobactericidal activities in macrophages. Infect Immun. 1992 Oct. 60(10):4245-52. [QxMD MEDLINE Link].

12. Newman GW, Guarnaccia JR, Vance EA 3rd, et al. Interleukin-12 enhances antigen-specific proliferation of peripheral blood mononuclear cells from HIV-positive and negative donors in response to Mycobacterium avium. AIDS. 1994 Oct. 8(10):1413-9. [QxMD MEDLINE Link].

13. Frucht DM, Holland SM. Defective monocyte costimulation for IFN-gamma production in familialdisseminated Mycobacterium avium complex infection: abnormal IL-12regulation. J Immunol. 1996 Jul 1. 157(1):411-6. [QxMD MEDLINE Link].

14. Bermudez LE, Wu M, Young LS. Interleukin-12-stimulated natural killer cells can activate humanmacrophages to inhibit growth of Mycobacterium avium. Infect Immun. 1995 Oct. 63(10):4099-104. [QxMD MEDLINE Link].

15. Chin DP, Hopewell PC. Mycobacterium avium complex in the respiratory or gastrointestinal tract precedes MAC bacteremia. Front Mycobacteria. 1992. 15.

16. Inderlied CB, Kemper CA, Bermudez LE. The Mycobacterium avium complex. Clin Microbiol Rev. 1993 Jul. 6(3):266-310. [QxMD MEDLINE Link].

17. Petrofsky M, Bermudez LE. CD4+ T cells but Not CD8+ or gammadelta+ lymphocytes are required for host protection against Mycobacterium avium infection and dissemination through the intestinal route. Infect Immun. 2005 May. 73(5):2621-7. [QxMD MEDLINE Link].

18. Levin M, Newport MJ, D'Souza S, et al. Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene?. Lancet. 1995 Jan 14. 345(8942):79-83. [QxMD MEDLINE Link].

19. Pierre-Audigier C, Jouanguy E, Lamhamedi S, et al. Fatal disseminated Mycobacterium smegmatis infection in a child withinherited interferon gamma receptor deficiency. Clin Infect Dis. 1997 May. 24(5):982-4. [QxMD MEDLINE Link].

20. Altare F, Jouanguy E, Lamhamedi-Cherradi S, et al. A causative relationship between mutant IFNgR1 alleles and impaired cellular response to IFN-gamma in a compound heterozygous child. Am J Hum Genet. 1998 Mar. 62(3):723-6. [QxMD MEDLINE Link].

21. Casanova JL, Newport M, Fischer A. Inherited Interferon-gamma receptor deficiency. Ochs HD et al, eds. Primary Immunodeficiency Diseases. Oxford, England: Oxford University Press; 1999. 209-21.

22. Dieudonne A, Oleske JM. Pediatric Human Immunodeficiency Virus Infection. Gorbach, Bartlett, Blacklow, eds. Infectious Diseases. 3rd ed. Lippincott Williams and Wilkins; 2004. 1056-99.

23. Salyer KE, Votteler TP, Dorman GW. Surgical management of cervical adenitis due to atypical mycobacteria inchildren. JAMA. 1968 Jun 17. 204(12):1037-40. [QxMD MEDLINE Link].

24. MacGregor RR, Hafner R, Wu JW, et al. Clinical, microbiological, and immunological characteristics in HIV-infected subjects at risk for disseminated Mycobacterium avium complex disease: an AACTG study. AIDS Res Hum Retroviruses. 2005 Aug. 21(8):689-95. [QxMD MEDLINE Link].

25. Merone A, Saggiomo G, Severino G, et al. [Buruli ulcer. A case report]. Minerva Pediatr. 2001 Dec. 53(6):587-90. [QxMD MEDLINE Link].

26. Thomssen H. [Buruli ulcer. A mycobacterial skin disease]. Hautarzt. 2002 May. 53(5):334-7. [QxMD MEDLINE Link].

27. Ackumey MM, Gyapong M, Pappoe M, Weiss MG. Help-seeking for pre-ulcer and ulcer conditions of Mycobacterium ulcerans disease (Buruli ulcer) in Ghana. Am J Trop Med Hyg. 2011 Dec. 85(6):1106-13. [QxMD MEDLINE Link]. [Full Text].

28. Phanzu DM, Mahema RL, Suykerbuyk P, Imposo DH, Lehman LF, Nduwamahoro E, et al. Mycobacterium ulcerans infection (Buruli ulcer) on the face: a comparative analysis of 13 clinically suspected cases from the Democratic Republic of Congo. Am J Trop Med Hyg. 2011 Dec. 85(6):1100-5. [QxMD MEDLINE Link]. [Full Text].

29. Dankner WM, Lindsey JC, Levin MJ, et al. Correlates of opportunistic infections in children infected with the humanimmunodeficiency virus managed before highly active antiretroviraltherapy. Pediatr Infect Dis J. 2001 Jan. 20(1):40-8. [QxMD MEDLINE Link].

30. Puthanakit T, Oberdorfer P, Akarathum N, et al. Immune reconstitution syndrome after highly active antiretroviral therapy in human immunodeficiency virus-infected thai children. Pediatr Infect Dis J. 2006 Jan. 25(1):53-8. [QxMD MEDLINE Link].

31. Johann-Liang R, Cervia JS, Noel GJ. Characteristics of human immunodeficiency virus-infected children at the time of death: an experience in the 1990s. Pediatr Infect Dis J. 1997 Dec. 16(12):1145-50. [QxMD MEDLINE Link].

32. Keller C, Kirkpatrick S, Lee K, et al. Disseminated Mycobacterium avium complex presenting as hematochezia in an infant with rapidly progressive acquired immunodeficiency syndrome. Pediatr Infect Dis J. 1996 Aug. 15(8):713-5. [QxMD MEDLINE Link].

33. Centers for Disease Control and Prevention. 2001 USPHS/IDSA guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus. MMWR. November 28, 2001.

34. Rutstein RM, Cobb P, McGowan KL, et al. Mycobacterium avium intracellulare complex infection in HIV-infected children. AIDS. 1993 Apr. 7(4):507-12. [QxMD MEDLINE Link].

35. Le Bourgeois M, Sermet-Gaudelus I, Catherinot E, Gaillard JL. [Nontuberculous mycobacteria in cystic fibrosis]. Arch Pediatr. 2005 Aug. 12 Suppl 2:S117-21. [QxMD MEDLINE Link].

36. Mussaffi H, Rivlin J, Shalit I, et al. Nontuberculous mycobacteria in cystic fibrosis associated with allergic bronchopulmonary aspergillosis and steroid therapy. Eur Respir J. 2005 Feb. 25(2):324-8. [QxMD MEDLINE Link].

37. Horsburgh CR Jr, Caldwell MB, Simonds RJ. Epidemiology of disseminated nontuberculous mycobacterial disease in children with acquired immunodeficiency syndrome. Pediatr Infect Dis J. 1993 Mar. 12(3):219-22. [QxMD MEDLINE Link].

38. Hoyt L, Oleske J, Holland B, Connor E. Nontuberculous mycobacteria in children with acquired immunodeficiency syndrome. Pediatr Infect Dis J. 1992 May. 11(5):354-60. [QxMD MEDLINE Link].

39. Hartmann P, Plum G. Immunological defense mechanisms in tuberculosis and MAC-infection. Diagn Microbiol Infect Dis. 1999 Jun. 34(2):147-52. [QxMD MEDLINE Link].

40. O'Brien RJ. The epidemiology of nontuberculous mycobacterial disease. Clin Chest Med. 1989 Sep. 10(3):407-18. [QxMD MEDLINE Link].

41. Schonell ME, Crofton JW, Stuart AE, Wallace A. Disseminated infection with Mycobacterium avium: I. Clinical features,treatment and pathology. Tubercle. 1968 Mar. 49(1):12-30. [QxMD MEDLINE Link].

42. Dieudonne A, McSherry, GD, Holland B. Clinical outcome and survival time in a cohort of HIV-infected children with atypical mycobacterial infections. Abstract Book. Annual Meeting of Society of Pediatric Research. 1997. Abstract 697:

43. Dieudonne A. Mycobacterium avium complex in HIV-infected infants and adolescents. Medical CME Program. Medical Word Communications. 1996. 8-10:

44. Kayal JD, McCall CO. Sporotrichoid cutaneous Mycobacterium avium complex infection. J Am Acad Dermatol. 2002 Nov. 47(5 Suppl):S249-50. [QxMD MEDLINE Link].

45. Astagneau P, Desplaces N, Vincent V, et al. Mycobacterium xenopi spinal infections after discovertebral surgery: investigation and screening of a large outbreak. Lancet. 2001 Sep 1. 358(9283):747-51. [QxMD MEDLINE Link].

46. Brutus JP, Baeten Y, Chahidi N, et al. Atypical mycobacterial infections of the hand: report of eight cases and literature review. Chir Main. 2001 Aug. 20(4):280-6. [QxMD MEDLINE Link].

47. Arend SM, Janssen R, Gosen JJ, et al. Multifocal osteomyelitis caused by nontuberculous mycobacteria in patients with a genetic defect of the interferon-gamma receptor. Neth J Med. 2001 Sep. 59(3):140-51. [QxMD MEDLINE Link].

48. Nakamura T, Yamamura Y, Tsuruta T, et al. Mycobacterium kansasii arthritis of the foot in a patient with systemic lupus erythematosus. Intern Med. 2001 Oct. 40(10):1045-9. [QxMD MEDLINE Link].

49. Villella A, Picard C, Jouanguy E, et al. Recurrent Mycobacterium avium osteomyelitis associated with a novel dominant interferon gamma receptor mutation. Pediatrics. 2001 Apr. 107(4):E47. [QxMD MEDLINE Link].

50. Lidar M, Elkayam O, Goodwin D, et al. Protracted Mycobacterium kansasii carpal tunnel syndrome and tenosynovitis. Isr Med Assoc J. 2003 Jun. 5(6):453-4. [QxMD MEDLINE Link].

51. De Smet L. Mycobacterium marinum infections of the hand: a report of three cases. Acta Chir Belg. 2008 Nov-Dec. 108(6:779-82. [QxMD MEDLINE Link].

52. Tigges F, Bauer A, Hochauf K, Meurer M. Sporotrichoid atypical cutaneous infection caused by Mycobacterium marinum. Acta Dermatovenerol Alp Panonica Adriat. 2009 Mar. 18(1):31-4 [PubMed - in process]. [QxMD MEDLINE Link].

53. Azzam HC, Gahunia MK, Sae-Tia, Santoro J. Mycobacterium avium--associated typhlitis mimicking appendicitis in an immunocompetent host. Am J Med Sci. 2009 Mar. 337(3):218-20. [QxMD MEDLINE Link].

54. Thaunat O, Morelon E, Stern M, et al. Mycobacterium xenopi pulmonary infection in two renal transplant recipients under sirolimus therapy. Transpl Infect Dis. 2004 Dec. 6(4):179-82. [QxMD MEDLINE Link].

55. Stelzmueller I, Dunst KM, Wiesmayr S, et al. Mycobacterium chelonae skin infection in kidney-pancreas recipient. Emerg Infect Dis. 2005 Feb. 11(2):352-4. [QxMD MEDLINE Link].

56. Wright HL, Thomson RM, Reid AB, Carter R, Bartley PB, Newton P, et al. Rapidly growing mycobacteria associated with laparoscopic gastric banding, Australia, 2005-2011. Emerg Infect Dis. 2014 Oct. 20(10):1612-9. [QxMD MEDLINE Link]. [Full Text].

57. Hackethal V. Gastric Banding Linked to Mycobacterium Infections. Medscape Medical News. Available at http://www.medscape.com/viewarticle/831462. Accessed: January 7, 2015.

58. Havlir D, Elnner JJ. Mycobacterium avium complex. Principle and Practice of Infectious Diseases. New York, NY: Churchill Livingstone; 2000. Vol 2: 2616-30.

59. Chaisson RE, Moore RD, Richman DD, et al. Incidence and natural history of Mycobacterium avium-complex infections inpatients with advanced human immunodeficiency virus disease treated withzidovudine. The Zidovudine Epidemiology Study Group. Am Rev Respir Dis. 1992 Aug. 146(2):285-9. [QxMD MEDLINE Link].

60. Lim SD, Todd J, Lopez J, et al. Genotypic identification of pathogenic Mycobacterium species by using a nonradioactive oligonucleotide probe. J Clin Microbiol. 1991 Jun. 29(6):1276-8. [QxMD MEDLINE Link].

61. Phillips P, Zala C, Rouleau D. Mycobacterial lymphadenitis: Can highly active antiretroviral therapy (HAART) unmask subclinical infection? Abstract 351. In: Program and Abstracts of the 4th Conference on Retroviruses and Opportunistic Infections. January 22-26, 1997:

62. Race EM, Adelson-Mitty J, Kriegel GR, et al. Focal mycobacterial lymphadenitis following initiation ofprotease-inhibitor therapy in patients with advanced HIV-1 disease. Lancet. 1998 Jan 24. 351(9098):252-5. [QxMD MEDLINE Link].

63. Kaplan MH. Mycobacterium avium-intracellulare (MAIS) reversal syndrome set off by highly active and anti-retroviral therapy (HAART). Improved immunity is not always good but it is better than no immunity. Abstract 726. In: Program and Abstracts of the 5th Conference. Alexandria, Va: Foundation for Retrovirology and Human Health. February 1-5, 1998:

64. Shafran SD. Prevention and treatment of disseminated Mycobacterium avium complexinfection in human immunodeficiency virus-infected individuals. Int J Infect Dis. 1998 Jul-Sep. 3(1):39-47. [QxMD MEDLINE Link].

65. Wallace RJ, Musser JM, Hull SI, et al. Diversity and sources of rapidly growing mycobacteria associated with infections following cardiac surgery. J Infect Dis. 1989 Apr. 159(4):708-16. [QxMD MEDLINE Link].

66. American Academy of Pediatrics. Diseases caused by nontuberculous Mycobacteria. Pickering LK, ed. 2006 Red Book: Report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2006.

67. Marras TK, Campitelli MA, Kwong JC, Lu H, Brode SK, Marchand-Austin A, et al. Risk of nontuberculous mycobacterial pulmonary disease with obstructive lung disease. Eur Respir J. 2016 Sep. 48 (3):928-31. [QxMD MEDLINE Link].

68. Stone AB, Schelonka RL, Drehner DM, et al. Disseminated Mycobacterium avium complex in non-human immunodeficiency virus-infected pediatric patients. Pediatr Infect Dis J. 1992 Nov. 11(11):960-4. [QxMD MEDLINE Link].

69. Dhooge I, Dhooge C, De Baets F, Van Cauwenberge P. Diagnostic and therapeutic management of atypical mycobacterial infections in children. Eur Arch Otorhinolaryngol. 1993. 250(7):387-91. [QxMD MEDLINE Link].

70. Da Silva Telles MA, Chimara E, Ferrazoli L, Riley LW. Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates. J Med Microbiol. 2005 Oct. 54(Pt 10):975-9. [QxMD MEDLINE Link].

71. Hartman TE, Swensen SJ, Williams DE. Mycobacterium avium-intracellulare complex: evaluation with CT. Radiology. 1993 Apr. 187(1):23-6. [QxMD MEDLINE Link].

72. Tamura A, Muraki K, Shimada M, et al. [Usefulness of bronchofiberscopy for the diagnosis of pulmonary non-tuberculous mycobacteriosis--an analysis mainly on pulmonary M. avium complex disease]. Kekkaku. 2008 Dec. 83(12):785-91. [QxMD MEDLINE Link].

73. Nyberg DA, Federle MP, Jeffrey RB, et al. Abdominal CT findings of disseminated Mycobacterium avium-intracellularein AIDS. AJR Am J Roentgenol. 1985 Aug. 145(2):297-9. [QxMD MEDLINE Link].

74. Robbins SL, Cotran RS, Kumar V. Pathologic basis of disease. 1984, Saunders, third edition. 300-350.

75. Torriani FJ, McCutchan JA, Bozzette SA, et al. Autopsy findings in AIDS patients with Mycobacterium avium complexbacteremia. J Infect Dis. 1994 Dec. 170(6):1601-5. [QxMD MEDLINE Link].

76. Rustom IK, Sandoe JA, Makura ZG. Paediatric neck abscesses: microbiology and management. J Laryngol Otol. 2007 Jun 11. 1-5. [QxMD MEDLINE Link].

77. Griffith DE, Brown BA, Girard WM, et al. Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. Clin Infect Dis. 2001 Jun 1. 32(11):1547-53. [QxMD MEDLINE Link].

78. Aberg JA, Yajko DM, Jacobson MA. Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy. J Infect Dis. 1998 Nov. 178(5):1446-9. [QxMD MEDLINE Link].

79. Gordin FM, Sullam PM, Shafran SD, et al. A randomized, placebo-controlled study of rifabutin added to a regimen of clarithromycin and ethambutol for treatment of disseminated infection with Mycobacterium avium complex. Clin Infect Dis. 1999 May. 28(5):1080-5. [QxMD MEDLINE Link].

80. Ramirez J, Mason C, Ali J, Lopez FA. Mycobacterium avium complex pulmonary disease: management options in HIV-negative patients. J La State Med Soc. 2008 Sep-Oct. 160(5):248-54; quiz 254, 293. [QxMD MEDLINE Link].

81. Huang JH, Kao PN, Adi V, Ruoss SJ. Mycobacterium avium-intracellulare pulmonary infection in HIV-negative patients without preexisting lung disease: diagnostic and management limitations. Chest. 1999 Apr. 115(4):1033-40. [QxMD MEDLINE Link]. [Full Text].

82. Schütte D, Umboock A, Pluschke G. Phagocytosis of Mycobacterium ulcerans in the course of rifampicin and streptomycin chemotherapy in Buruli ulcer lesions. Br J Dermatol. Feb. 2009. 273-283. [QxMD MEDLINE Link].

83. Kuwabara K, Tsuchiya T. [Clinical features and treatment history of clarithromycin resistance in M. avium-intracellulare complex pulmonary disease patients]. Nihon Kokyuki Gakkai Zasshi. 2007 Aug. 45(8):587-92. [QxMD MEDLINE Link].

84. Centers for Disease Control and Prevention. 2002 USPHS/IDSA guidelines for prevention of opportunistic infections in persons with HIV. MMWR. 2002. [Full Text].

85. El-Sadr WM, Burman WJ, Grant LB, et al. Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. N Engl J Med. 2000 Apr 13. 342(15):1085-92. [QxMD MEDLINE Link].

86. Hawkins CC, Gold JW, Whimbey E, et al. Mycobacterium avium complex infections in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1986 Aug. 105(2):184-8. [QxMD MEDLINE Link].

87. Wallace RJ Jr. Mycobacterium avium complex lung disease and women. Now an equal opportunity disease. Chest. 1994 Jan. 105(1):6-7. [QxMD MEDLINE Link].

88. Sohn CC, Schroff RW, Kliewer KE, et al. Disseminated Mycobacterium avium-intracellulare infection in homosexual men with acquired cell-mediated immunodeficiency: a histologic and immunologic study of two cases. Am J Clin Pathol. 1983 Feb. 79(2):247-52. [QxMD MEDLINE Link].

89. Horsburgh CR, Metchock B, Gordon SM, et al. Predictors of survival in patients with AIDS and disseminated Mycobacterium avium complex disease. J Infect Dis. 1994 Sep. 170(3):573-7. [QxMD MEDLINE Link].

90. Lewis LL, Butler KM, Husson RN, et al. Defining the population of human immunodeficiency virus-infected children at risk for Mycobacterium avium-intracellulare infection. J Pediatr. 1992 Nov. 121(5 Pt 1):677-83. [QxMD MEDLINE Link].

91. Jacobson MA, Hopewell PC, Yajko DM, et al. Natural history of disseminated Mycobacterium avium complex infection in AIDS. J Infect Dis. 1991 Nov. 164(5):994-8. [QxMD MEDLINE Link].

Arry Dieudonne, MD Associate Professor of Pediatrics, Division of Pulmonology, Allergy, Immunology and Infectious Diseases, Rutgers New Jersey Medical School; Clinical Director, Francois-Xavier Bagnold Center for Children, University Hospital

Arry Dieudonne, MD is a member of the following medical societies: American Academy of Pediatrics, American Medical Association, Pediatric Infectious Diseases Society

Disclosure: Nothing to disclose.

James M Oleske, MD, MPH François-Xavier Bagnoud Professor of Pediatrics, Director, Division of Pulmonary, Allergy, Immunology and Infectious Diseases, Department of Pediatrics, Rutgers New Jersey Medical School; Professor, Department of Quantitative Methods, Rutgers New Jersey Medical School

James M Oleske, MD, MPH is a member of the following medical societies: Academy of Medicine of New Jersey, American Academy of Allergy Asthma and Immunology, American Academy of Hospice and Palliative Medicine, American Association of Public Health Physicians, American College of Preventive Medicine, American Pain Society, Infectious Diseases Society of America, Infectious Diseases Society of New Jersey, Medical Society of New Jersey, Pediatric Infectious Diseases Society, Arab Board of Family Medicine, American Academy of Pain Management, National Association of Pediatric Nurse Practitioners, Association of Clinical Researchers and Educators, American Academy of HIV Medicine, American Thoracic Society, American Academy of Pediatrics, American Public Health Association, American Society for Microbiology, Infectious Diseases Society of America, Pediatric Infectious Diseases Society

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Professor of Pediatrics, Professor of Medicine, Rutgers New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, New York Academy of Medicine, Royal College of Physicians of Edinburgh, Sigma Xi

Disclosure: Nothing to disclose.

Mary L Windle, PharmD Adjunct Associate Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Nothing to disclose.

Mark R Schleiss, MD Minnesota American Legion and Auxiliary Heart Research Foundation Chair of Pediatrics, Professor of Pediatrics, Division Director, Division of Infectious Diseases and Immunology, Department of Pediatrics, University of Minnesota Medical School

Mark R Schleiss, MD is a member of the following medical societies: American Pediatric Society, Infectious Diseases Society of America, Pediatric Infectious Diseases Society, Society for Pediatric Research

Disclosure: Nothing to disclose.

Russell W Steele, MD Clinical Professor, Tulane University School of Medicine; Staff Physician, Ochsner Clinic Foundation

Russell W Steele, MD is a member of the following medical societies: American Academy of Pediatrics, American Association of Immunologists, American Pediatric Society, American Society for Microbiology, Infectious Diseases Society of America, Louisiana State Medical Society, Pediatric Infectious Diseases Society, Society for Pediatric Research, Southern Medical Association

Disclosure: Nothing to disclose.

Itzhak Brook, MD, MSc Professor, Department of Pediatrics, Georgetown University School of Medicine

Itzhak Brook, MD, MSc is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians-American Society of Internal Medicine, American Medical Association, American Society for Microbiology, Association of Military Surgeons of the US, Infectious Diseases Society of America, International Immunocompromised Host Society, International Society for Infectious Diseases, Medical Society of the District of Columbia, New York Academy of Sciences, Pediatric Infectious Diseases Society, Society for Experimental Biology and Medicine, Society for Pediatric Research, Southern Medical Association, Society for Ear, Nose and Throat Advances in Children, American Federation for Clinical Research, Surgical Infection Society, Armed Forces Infectious Diseases Society

Disclosure: Nothing to disclose.

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