Atypical Mycobacterial Infection Differential Diagnoses

Updated: Sep 22, 2023
  • Author: Arry Dieudonne, MD; Chief Editor: Russell W Steele, MD  more...
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Diagnostic Considerations

Rule out any malignant process such as lymphoma and metastatic Kaposi sarcoma and other nonmalignant etiologies, such as bacterial adenitis, mononucleosis, toxoplasmosis, tuberculous lymphadenitis, and catscratch disease in children with suppurative lymphadenitis or persistent generalized lymphadenopathies. [9] HIV infection per se may cause multiorgan involvement accompanied by all the systemic symptoms observed in disseminated M avium complex (MAC) disease. Other immunodeficiencies such as severe combined immunodeficiency and IFN-gamma receptor ligand-binding deficiency should be investigated, especially in patients without AIDS with disseminated MAC disease. [77]