Pediatric Lymphocytic Choriomeningitis Virus Medication

Updated: Aug 15, 2018
  • Author: J Michael Klatte, MD; Chief Editor: Russell W Steele, MD  more...
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Medication Summary

No specific treatment for lymphocytic choriomeningitis virus (LCMV) infection is available. Early data suggest that the virus is susceptible to ribavirin in vitro, but little information on the treatment of infected humans is available. Despite this, and despite the fact that no large-scale determination has been made regarding the efficacy of ribavirin use in transplant-acquired LCMV, the recommended treatment for these patients includes reduced immunosuppression and ribavirin. [3, 19]

In vitro studies on favipiravir (a compound shown to inhibit LCMV replication) and experimental pyrimidine biosynthesis inhibitors show promising potential for these agents as future LCMV treatment options in humans. [1, 20]