Anemia of Prematurity Clinical Presentation

Updated: Jan 08, 2016
  • Author: George Cassady, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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History and Physical Examination

Many clinical findings have been attributed to anemia of prematurity (AOP), but they are neither specific nor diagnostic. These symptoms may include the following:

  • Poor weight gain despite adequate caloric intake

  • Cardiorespiratory symptoms such as tachycardia, tachypnea, and flow murmurs

  • Decreased activity, lethargy, and difficulty with oral feeding

  • Pallor

  • Increase in apneic and bradycardic episodes, and worsened periodic breathing

  • Metabolic acidemia - Increased lactic acid secondary to increased cellular anaerobic metabolism in relatively hypoxic tissues