Neonatal Sepsis Questions & Answers

Updated: Jun 13, 2019
  • Author: Nathan S Gollehon, MD, FAAP; Chief Editor: Muhammad Aslam, MD  more...
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Questions & Answers

Overview

What is neonatal sepsis categorized?

What is early-onset neonatal sepsis categorized?

What is late-onset neonatal sepsis categorized?

What is the pathophysiology of neonatal sepsis?

What is the role of cellular immunity in the pathophysiology of neonatal sepsis?

What is the role of humoral immunity in the pathophysiology of neonatal sepsis?

What is the role of infection barriers in the pathophysiology of neonatal sepsis?

What is the role of the GI system in the pathophysiology of neonatal sepsis?

What is the role of ventriculitis in the pathophysiology of neonatal sepsis?

What is the role of arachnoiditis in the pathophysiology of neonatal sepsis?

What is the role of vasculitis in the pathophysiology of neonatal sepsis?

What is the role of cerebral edema in the pathophysiology of neonatal sepsis?

What is the role of infarction in the pathophysiology of neonatal sepsis?

What causes early-onset neonatal sepsis?

What causes late-onset neonatal sepsis?

What causes neonatal meningitis-related sepsis?

What is the prevalence of neonatal sepsis?

Which neonates have the greatest risk for neonatal sepsis?

What is the prognosis of neonatal sepsis?

Presentation

What are the risk factors for neonatal sepsis?

What is the role of maternal GBS status in the etiology of neonatal sepsis?

What is the role of premature rupture of membranes in the etiology of neonatal sepsis?

What is the role of prematurity in the etiology of neonatal sepsis?

What is the role of chorioamnionitis in the etiology of neonatal sepsis?

What are the signs and symptoms of neonatal sepsis?

Which physical findings are characteristic of intrauterine infection-caused neonatal sepsis?

Which physical findings are characteristic of intrapartum infection-caused neonatal sepsis?

Which physical findings are characteristic of postnatal infection-caused neonatal sepsis?

What are the cardiac signs and symptoms of neonatal sepsis?

What are the metabolic signs and symptoms of neonatal sepsis?

What are the neurologic signs and symptoms of neonatal sepsis?

DDX

What are the differential diagnoses for Neonatal Sepsis?

Workup

How is neonatal sepsis diagnosed?

What is the role of cultures in the workup of neonatal sepsis?

What is the role of CBC count in the workup of neonatal sepsis?

Which lab findings are characteristic of neonatal sepsis?

What is the role of coagulation studies in the workup of neonatal sepsis?

What is the role of lumbar puncture in the workup of neonatal sepsis?

What is the role of CSF analysis in the workup of neonatal sepsis?

What is the role of HSV PCR testing in the workup of neonatal sepsis?

What is the role of chest radiography in the workup of neonatal sepsis?

What is the role of CT scanning and MRI in the workup of neonatal sepsis?

What is the role of ultrasonography in the workup of neonatal sepsis?

Treatment

How is neonatal sepsis treated?

Which medical therapies are used in the treatment of neonatal sepsis?

What is the role of antibiotics in the treatment of neonatal sepsis?

How is meningitis treated in neonates with sepsis?

Which therapies have been investigated for the treatment of neonatal sepsis?

What is the role of granulocyte transfusion in the treatment of neonatal sepsis?

What is the role of IVIg infusion in the treatment of neonatal sepsis?

What is the role of recombinant human cytokine administration in the treatment of neonatal sepsis?

How is neonatal sepsis prevented?

Which specialist consultations are beneficial to patients with neonatal sepsis?

What is included in the long-term monitoring of neonatal sepsis?

Medications

What is the role of medications in the treatment of neonatal sepsis?

Which medications in the drug class Antifungals, Systemic are used in the treatment of Neonatal Sepsis?

Which medications in the drug class Antivirals, Other are used in the treatment of Neonatal Sepsis?

Which medications in the drug class Antibiotics, Other are used in the treatment of Neonatal Sepsis?