Neonatal Hypertension Differential Diagnoses

Updated: Jan 03, 2016
  • Author: Joseph Flynn, MD, MS; Chief Editor: Ted Rosenkrantz, MD  more...
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DDx

Diagnostic Considerations

Cardiac conditions to consider in the differential diagnosis of neonatal hypertension include thoracic aortic coarctation. Renovascular conditions to consider in the differential diagnosis include the following:

  • Thromboembolism

  • Renal artery stenosis

  • Midabdominal aortic coarctation

  • Renal venous thrombosis

  • Compression of renal artery

  • Idiopathic arterial calcification

  • Congenital rubella syndrome

Renal parenchymal diseases to consider in the differential diagnosis of neonatal hypertension include the following:

  • Polycystic kidney disease

  • Multicystic dysplastic kidney disease

  • Tuberous sclerosis

  • Ureteropelvic junction obstruction

  • Acute tubular necrosis

  • Cortical necrosis

  • Interstitial nephritis

  • Hemolytic-uremic syndrome

Pulmonary conditions to consider in the differential diagnosis of neonatal hypertension include the following:

  • Bronchopulmonary dysplasia

  • Pneumothorax

Endocrine conditions to consider in the differential diagnosis of neonatal hypertension include the following:

  • Congenital adrenal hyperplasia

  • Hyperaldosteronism

  • Hyperthyroidism

  • Pseudohypoaldosteronism type II

Medications/intoxications to consider in the differential diagnosis of neonatal hypertension include the following:

  • Dexamethasone

  • Adrenergic agents

  • Vitamin D intoxication

  • Theophylline

  • Caffeine

  • Pancuronium

  • Phenylephrine

  • Maternal cocaine or heroin use

Tumors that should be considered in the differential diagnosis of neonatal hypertension include the following:

  • Neoplasia

  • Wilms tumor

  • Mesoblastic nephroma

  • Neuroblastoma

  • Pheochromocytoma

Neurologic conditions to consider in the differential diagnosis of neonatal hypertension include the following:

  • Pain

  • Intracranial hypertension

  • Seizures

  • Familial dysautonomia

  • Subdural hematoma

Miscellaneous conditions to consider in the differential diagnosis of neonatal hypertension include the following:

  • Closure of abdominal wall defect

  • Adrenal hemorrhage

  • Hypercalcemia

  • Traction

  • Extracorporeal membrane oxygenation

  • Birth asphyxia

  • Urologic neoplasms

Differential Diagnoses