Adipsia Medication

Updated: Dec 13, 2018
  • Author: Vikas R Dharnidharka, MD, MPH; Chief Editor: Craig B Langman, MD  more...
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Vasopressin analogs

Class Summary

These agents are indicated when diabetes insipidus coexists. Desmopressin is a synthetic antidiuretic hormone with actions that mimic vasopressin. It is used to treat diabetes insipidus, which deprives the kidney of its capacity to produce concentrated urine. This results in large volumes of dilute urine (polyuria) and excessive thirst (polydipsia). Elevated sodium serum concentrations may occur, but hypernatremia is more likely to be severe when fluid is restricted.

Desmopressin acetate (DDAVP)

Increases cellular permeability of collecting ducts, resulting in reabsorption of water by kidneys.