Hemorrhagic Fever With Renal Failure Syndrome Differential Diagnoses

Updated: Oct 31, 2023
  • Author: Rajendra Bhimma, MBChB, MD, PhD, DCH (SA), FCP(Paeds)(SA), MMed(Natal); Chief Editor: Craig B Langman, MD  more...
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Diagnostic Considerations

In high-risk geographic areas, hemorrhagic fever with renal failure syndrome (HFRS) should be included in the differential diagnosis of acute renal failure of uncertain cause associated with febrile illness, hemorrhagic phenomenon, or renal or hepatic dysfunction.

Also consider the following:

  • Spotted fevers

  • Murine typhus

  • Non-A, non-B hepatitis

  • Colorado tick fever

  • Septicemia

  • Heat stroke

  • Disseminated intravascular coagulation (DIC)

  • Scrub typhus

  • Acute kidney injury

  • Acute abdominal diseases

Differential Diagnoses