Myoglobinuria Follow-up

Updated: Jan 06, 2017
  • Author: Prasad Devarajan, MD, FAAP; Chief Editor: Craig B Langman, MD  more...
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Follow-up

Further Outpatient Care

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  • Patients may need extensive rehabilitation for muscle damage.

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Further Inpatient Care

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  • Hemodialysis or continuous veno-veno hemodialysis (CVVHD) may be needed to treat acute renal insufficiency in patients with myoglobinuria. Recovery often occurs in 10-14 days.

  • Electrolyte complications of rhabdomyolysis, including hyperkalemia and hypocalcemia, may need immediate treatment.

  • In the recovery phase, patients may develop hypercalcemia as calcium precipitated in damaged tissue returns to the circulation.

  • Long-term diuresis may cause hypokalemia.

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Deterrence/Prevention

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  • Patients with metabolic muscle diseases must avoid trauma, overexertion, dehydration, and heat injuries.

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Complications

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  • The most serious complication of myoglobinuria is acute renal failure.

  • Other complications can result from renal shutdown or from the intracellular products released into the system by rhabdomyolysis.

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Prognosis

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  • Patients with uncomplicated cases of myoglobinuria recover without sequelae.

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Patient Education

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  • Patients who develop exercise-induced rhabdomyolysis need education in maintaining adequate fluid intake, in oral rehydration, and in pacing their exercise in hot weather or extreme conditions.

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