Wrist Dislocation in Sports Medicine Medication

Updated: Feb 26, 2015
  • Author: Kadeer M Halimi, DO; Chief Editor: Sherwin SW Ho, MD  more...
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Medication

Medication Summary

Pain control is essential in providing quality patient care to those with wrist dislocations. Pain control ensures patient comfort and aids physical therapy regimens.

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Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Class Summary

NSAIDs are most commonly used for the relief of mild to moderate pain. The effects of these agents in the treatment of pain tend to be patient specific, yet ibuprofen is usually the drug of choice (DOC) for initial therapy. Other NSAIDs may also be used.

Cyclooxygenase-2 (COX-2) inhibitors may be considered in patients with adverse effects to the NSAIDs discussed here.

Ibuprofen (Ibuprin, Advil, Motrin)

DOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Flurbiprofen (Ansaid)

May inhibit the cyclooxygenase enzyme, which, in turn, inhibits prostaglandin biosynthesis. These effects may result in analgesic, antipyretic, and anti-inflammatory activities.

Ketoprofen (Oruvail, Orudis, Actron)

For the relief of mild to moderate pain and inflammation. Small initial doses are indicated in small or elderly patients and in those with renal or liver disease.

Doses >75 mg do not increase the therapeutic effects. Administer high doses with caution, and closely observe patient for response.

Naproxen (Naprelan, Aleve, Anaprox, Naprosyn)

For the relief of mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing the activity of cyclooxygenase, which is responsible for prostaglandin synthesis.

Celecoxib (Celebrex)

Inhibits primarily COX-2. COX-2 is considered an inducible isoenzyme, induced during pain and inflammatory stimuli. Inhibition of COX-1 may contribute to NSAID GI toxicity. At therapeutic concentrations, COX-1 isoenzyme is not inhibited; thus, GI toxicity may be decreased. Seek the lowest dose of celecoxib for each patient.

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Analgesics

Class Summary

Pain control is essential to providing the quality of care for patients with wrist dislocations. Pain control ensures the patient's comfort and aids in physical therapy regimens. Many analgesics have sedating properties that benefit patients with fractures. Hydrocodone and oxycodone preparations are generally more effective and better tolerated than other narcotic-acetaminophen combinations, such as those containing codeine.

Codeine/acetaminophen (Tylenol-3)

Indicated for the treatment of mild to moderate pain.

Hydrocodone and acetaminophen (Vicodin, Norcet, Lortab, Lorcet-HD)

Drug combination indicated for moderate to severe pain.

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