Lymphohistiocytosis (Hemophagocytic Lymphohistiocytosis) Follow-up

Updated: Feb 26, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Further Outpatient Care

Supportive care is needed to ensure that the patient with hemophagocytic lymphohistiocytosis (HLH) remains stable until a bone marrow donor can be found. This includes transfusions of red blood cells, platelets, and fresh frozen plasma, as well as nutritional support in addition to the treatment protocol. [50]

Patients should be continually monitored for evidence of infection because of their immunosuppressed state. Be aware of the possibility of underlying malignancy.

Biopsies and diagnostic cytogenetics may be needed in addition to selective radiographic imaging. [32]