Pediatric Neuroblastoma Questions & Answers

Updated: Oct 09, 2017
  • Author: Norman J Lacayo, MD; Chief Editor: Max J Coppes, MD, PhD, MBA  more...
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Questions & Answers

Overview

What is pediatric neuroblastoma?

What are the chromosomal and molecular markers of pediatric neuroblastoma?

What are the most common anatomic sites for pediatric neuroblastoma?

How are pediatric neuroblastoma detected?

What is the pathophysiology of pediatric neuroblastoma

What are the histologic characteristics of pediatric neuroblastoma?

What is the Shimada histopathologic classification system of pediatric neuroblastoma?

What is the US prevalence of pediatric neuroblastoma?

What is the global prevalence of pediatric neuroblastoma?

What are the mortality rates of pediatric neuroblastoma?

What is the morbidity associated with pediatric neuroblastoma?

What are the racial predilections of pediatric neuroblastoma?

What are the sexual predilections of pediatric neuroblastoma?

Which age groups have the highest prevalence of pediatric neuroblastoma?

Presentation

Which clinical history findings are characteristic of pediatric neuroblastoma?

Which physical findings are characteristic of pediatric neuroblastoma?

What causes pediatric neuroblastoma?

DDX

What are the differential diagnoses for Pediatric Neuroblastoma?

Workup

What is the role of lab tests in the workup of pediatric neuroblastoma?

What is the role of imaging studies in the workup of pediatric neuroblastoma?

Which baseline studies are conducted prior to treatment of pediatric neuroblastoma with anthracyclines?

What is the role of biopsy in the workup of pediatric neuroblastoma?

How is pediatric neuroblastoma diagnosed?

How is pediatric neuroblastoma staged?

Treatment

How is pediatric neuroblastoma treated?

How is low-risk pediatric neuroblastoma treated?

How is intermediate-risk pediatric neuroblastoma treated?

How is high-risk pediatric neuroblastoma treated?

Which medications are being investigated for the treatment of pediatric neuroblastoma?

What is the role of surgery in the treatment of pediatric neuroblastoma?

Which specialist consultations are beneficial to patients with pediatric neuroblastoma?

Which dietary modifications are used in the treatment of pediatric neuroblastoma?

Which activity modifications are used in the treatment of pediatric neuroblastoma?

Medications

What is the role of medications in the treatment of pediatric neuroblastoma?

Which medications in the drug class Antineoplastics, Monoclonal Antibody are used in the treatment of Pediatric Neuroblastoma?

Which medications in the drug class Chemoprotective Agents are used in the treatment of Pediatric Neuroblastoma?

Which medications in the drug class Colony-stimulating Factors are used in the treatment of Pediatric Neuroblastoma?

Which medications in the drug class Antineoplastic Agents are used in the treatment of Pediatric Neuroblastoma?

Follow-up

What is included in the long-term monitoring of pediatric neuroblastoma?

When is inpatient care indicated for the treatment of pediatric neuroblastoma?

Which medications are used in the treatment of pediatric neuroblastoma?

What is the role of a primary care provider in the treatment of pediatric neuroblastoma?

How is pediatric neuroblastoma prevented?

What are the possible complications of pediatric neuroblastoma?

Which factors are used to determine response to treatment and prognosis of pediatric neuroblastoma?

What is the prognosis of pediatric neuroblastoma?

What are the criteria used to evaluate response to treatment in pediatric neuroblastoma?

What is included in patient education about pediatric neuroblastoma?