Ewing Sarcoma Differential Diagnoses

Updated: Mar 03, 2021
  • Author: Jeffrey A Toretsky, MD; Chief Editor: Vikramjit S Kanwar, MBBS, MBA, MRCP(UK)  more...
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Diagnostic Considerations

Because Ewing sarcomas are rare, they are often not considered in a differential diagnosis until biopsy reveals a neoplasm known as a small round blue cell tumor. Malignancy is usually in the differential diagnosis before biopsy. For this reason, consultation with a pediatric oncologist is critical.

Ewing sarcoma should be considered in the differential diagnosis if a patient aged 10-30 years has a soft tissue or bony mass that causes the physician to consider the presence of a neoplasm.

Differential Diagnoses